DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10931 and WDR88

DIOPT Version :9

Sequence 1:NP_611261.1 Gene:CG10931 / 37024 FlyBaseID:FBgn0034274 Length:345 Species:Drosophila melanogaster
Sequence 2:NP_775750.3 Gene:WDR88 / 126248 HGNCID:26999 Length:472 Species:Homo sapiens


Alignment Length:306 Identity:75/306 - (24%)
Similarity:126/306 - (41%) Gaps:68/306 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 LLGHSGCVTGLKFSSNGENLVSSSGDRLLKLWDL---SATRCIQSLAGHGDGVNDVAWSAAG--- 110
            |.||...|:...|..:...|:|.|.|..:||||.   |..|..:    |......|..|..|   
Human    98 LSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFE----HRPKAPVVECSITGDSS 158

  Fly   111 LIASCSDDMTVRLWDARS---------------------------------KLCVK--------- 133
            .:.:.|.|.|||.||..:                                 .:|:.         
Human   159 RVIAASYDKTVRAWDLETGKLLWKVRYDTFIVSCKFSPDGKYVVSGFDVDHGICIMDAENITTVS 223

  Fly   134 -VLEGHSRYSFSCCFNPQANLLASTSFDETVRLWDVRTGKT-LKIVHAHQDPITSVDFHRDGNIF 196
             :.:.|:|...||||:|.:..:||.|.|..:::|||.:..| |.|..||.:.|::..|...|:..
Human   224 VIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFL 288

  Fly   197 VTSSYDGLVRLWDSSTGH-----VLKTLVDVDNIPVGYVKFSPNGRYILSSTLNNTLRLWNYKKP 256
            .|||:|..:::|:..||.     ...||:......|....|:.:..:::|...:.|:.:|:..:.
Human   289 CTSSWDKNLKIWNVHTGEFRNCGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEG 353

  Fly   257 KCMRTYRGH---LNEFYCSNSNFSTTGGIWIVSGSEDNTLCIWNLQ 299
            ....:.:||   :.:...||:.      .||:|.|:|.|:.:||::
Human   354 YRKLSLKGHNDWVMDVAISNNK------KWILSASKDRTMRLWNIE 393

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10931NP_611261.1 WD40 <48..341 CDD:225201 75/306 (25%)
WD40 49..341 CDD:238121 75/306 (25%)
WD40 repeat 59..96 CDD:293791 12/39 (31%)
WD40 repeat 102..137 CDD:293791 11/80 (14%)
WD40 repeat 142..178 CDD:293791 15/36 (42%)
WD40 repeat 185..220 CDD:293791 10/39 (26%)
WD40 repeat 227..263 CDD:293791 5/35 (14%)
WD40 repeat 271..309 CDD:293791 10/29 (34%)
WD40 repeat 314..340 CDD:293791
WDR88NP_775750.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22
WD40 96..391 CDD:238121 73/302 (24%)
WD40 97..>398 CDD:225201 75/306 (25%)
WD 1 100..139 13/38 (34%)
WD40 repeat 106..142 CDD:293791 11/39 (28%)
WD 2 143..182 10/38 (26%)
WD40 repeat 148..181 CDD:293791 10/32 (31%)
WD 3 184..224 1/39 (3%)
WD40 repeat 190..226 CDD:293791 1/35 (3%)
WD 4 228..267 15/38 (39%)
WD40 repeat 233..270 CDD:293791 15/36 (42%)
WD 5 271..310 12/38 (32%)
WD40 repeat 276..317 CDD:293791 11/40 (28%)
WD 6 319..358 5/38 (13%)
WD40 repeat 324..348 CDD:293791 4/23 (17%)
WD 7 361..400 12/39 (31%)
WD40 repeat 366..390 CDD:293791 8/29 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 447..472
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0266
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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