Protein Alignment PIG-A and ALG2

DIOPT Version :9

• Sequence 1: NP_001286547.1
• Gene: PIG-A / 37020
• FlyBaseID: FBgn0034270
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_149078.1
• Gene: ALG2 / 85365
• HGNCID: 23159
• Length: 416
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 75/402 - (18%)
• Similarity: 137/402 - (34%)
• Gaps: 122/402 - (30%)

  Fly     9 FFYP--SIGGVEEHVYNLSQMLLSLGHKIVVLTHAY--GDC-----------------SGIRY-- 50
            |.:|  .:||.|..|.:.:..|.:.|..:.:.|..|  |.|                 .|:.:
Human    19 FLHPDLGVGGAERLVLDAALALQARGCSVKIWTAHYDPGHCFAESRELPVRCAGDWLPRGLGWGG 83

  Fly    51 ----VTGYLKVYYLPIKVCY-NQCILPTAVCN-----VPMLRAVLLRERVEVVHGHSAFSALAHE 105
                |..|:::.:|.:.|.: ........||:     :|:.|....|:::
Human    84 RGAAVCAYVRMVFLALYVLFLADEEFDVVVCDQVSACIPVFRLARRRKKI--------------- 133

  Fly   106 ALMVGSLLGLKTVFTDHSLFGFADLSAALTNNLL------------EVNLGMVNHAICVSHIGKE 158
                        :|..|    |.||.....::.|            |...||   |.|:    ..
Human   134 ------------LFYCH----FPDLLLTKRDSFLKRLYRAPIDWIEEYTTGM---ADCI----LV 175

  Fly   159 NTVLRARVAKHRVSVIPNAVDTALFTPDPQQRPSNDIINI--VVASRL--VYRKGIDLLAGIIPR 219
            |:...|.|.|.....:.:.....|:       ||.::.:.  ||..:|  :..||...|...|.|
Human   176 NSQFTAAVFKETFKSLSHIDPDVLY-------PSLNVTSFDSVVPEKLDDLVPKGKKFLLLSINR 233

  Fly   220 FKNTPNINFIIVGDGPKRDLLEEIREKTNMQ--ERVQMVGA----------VEHNRVRDFLVR-- 270
            ::...|:...:       :.|.::|.:...|  |||.::.|          |||.:....:|:
Human   234 YERKKNLTLAL-------EALVQLRGRLTSQDWERVHLIVAGGYDERVLENVEHYQELKKMVQQS 291

  Fly   271 ---GHIFLNTSLTEAYCMAIVEAASCGLQVVSTSVGGIPEVLPKSLILLAEPEIDAIYAAILIAI 332
               .::....|.::...::::.:.:|.|...|....||   :|...:.:..|.|.......|.:|
Human   292 DLGQYVTFLRSFSDKQKISLLHSCTCVLYTPSNEHFGI---VPLEAMYMQCPVIAVNSGGPLESI 353

  Fly   333 DRHRKSSFKVSP 344
            | |..:.|...|
Human   354 D-HSVTGFLCEP 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-A	NP_001286547.1	RfaB	1..309	CDD:223515	66/365 (18%)
		GT1_PIG-A_like	2..451	CDD:99970	75/402 (19%)
ALG2	NP_149078.1	GT1_ALG2_like	16..407	CDD:99977	75/402 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810