Protein Alignment PIG-A and GSY2

DIOPT Version :10

• Sequence 1: NP_611257.1
• Gene: PIG-A / 37020
• FlyBaseID: FBgn0034270
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_013359.1
• Gene: GSY2 / 850962
• SGDID: S000004248
• Length: 705
• Species: Saccharomyces cerevisiae
• Alignment Length: 490
• Identity: 103/490 - (21%)
• Similarity: 175/490 - (35%)
• Gaps: 156/490 - (31%)

  Fly     3 ICMVSDF-FYPSIGGVE-EH------VYNLSQMLLSLGHKIVVLTHAYGDCSGIRYVTGYLKVYY 59
            :|....| ||..:..|: :|      :|:...:..:..|...|.|       .:..:|.:...:.
Yeast   201 LCASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFT-------TVSQITAFEAEHL 258

  Fly    60 LPIKVCYNQCILPTAVCNVPMLRA--------VLLRERV-EVVHGH------------------- 96
            |..|   ...|||..: ||...:|        .|.:|:: :.|.||
Yeast   259 LKRK---PDGILPNGL-NVIKFQAFHEFQNLHALKKEKINDFVRGHFHGCFDFDLDNTLYFFIAG 319

  Fly    97 -------------SAFSALAHEALMVGSLLGLKTV------------FTDHSLFGFADLSAALTN 136
                         .|.:.|.:...:.||   .|||            ||..:|.|.|:: .||.|
Yeast   320 RYEYKNKGADMFIEALARLNYRLKVSGS---KKTVVAFIVMPAKNNSFTVEALKGQAEV-RALEN 380

  Fly   137 NLLEVNLGMVNHAICVSHIGKENTVLRARVAKHRVSVIPNAVDTALFTPDPQQRPSNDIINIVVA 201
            .:.||          .:.|||       |:..|.:....|.:.|.|.|...:...|:|.:
Yeast   381 TVHEV----------TTSIGK-------RIFDHAIRYPHNGLTTELPTDLGELLKSSDKV----- 423

  Fly   202 SRLVYRKGIDLLAGIIPRFKNTPNINFIIVGDGPKRDL-LEEIREK---TNMQERVQMVGAVE-- 260
              ::.|:   :||...|..:..|.:...:|.|.  .|| |.:||:.   .:..:||:|:...|
Yeast   424 --MLKRR---ILALRRPEGQLPPIVTHNMVDDA--NDLILNKIRQVQLFNSPSDRVKMIFHPEFL 481

  Fly   261 --HNRV----RDFLVRG-HIFLNTSLTEAYCMAIVEAASCGLQVVSTSVGGIPEVLPKSLILLAE 318
              :|.:    .|..||| |:.:..|..|.:.....|....|:..::|:|.|....: :.||...:
Yeast   482 NANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGAYM-EDLIETNQ 545

  Fly   319 PEIDAIYAAILIAIDRHRKSSFKVSPSVGNGHLASDANGKVKRRRRRKVDTPISPTQLPAVSAPP 383
            .:...||     .:||..|     :|......|.......||:.||:::
Yeast   546 AKDYGIY-----IVDRRFK-----APDESVEQLVDYMEEFVKKTRRQRI---------------- 584

  Fly   384 ADQNSSTEPVMCPYRCNELVETLYNWEDVALRTVK 418
             :|.:.||      |.::|::    |:.:.|..||
Yeast   585 -NQRNRTE------RLSDLLD----WKRMGLEYVK 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-A	NP_611257.1	GT4_PIG-A-like	2..451	CDD:340827	103/490 (21%)
GSY2	NP_013359.1	GT3_GSY2-like	7..616	CDD:340824	103/490 (21%)