Protein Alignment PIG-A and GYS2

DIOPT Version :9

• Sequence 1: NP_001286547.1
• Gene: PIG-A / 37020
• FlyBaseID: FBgn0034270
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_068776.2
• Gene: GYS2 / 2998
• HGNCID: 4707
• Length: 703
• Species: Homo sapiens
• Alignment Length: 359
• Identity: 70/359 - (19%)
• Similarity: 127/359 - (35%)
• Gaps: 96/359 - (26%)

  Fly    81 LRAVLLRERVEVVHGHSAFSALAHEALMVGSLLG------LKTVFTDHSLFGFADLSAALTNNLL 139
            |.|..|:|..:...|....:........:|.:|.      :.|:||.|        :..|...|.
Human   158 LTAWFLKEVTDHADGKYVVAQFHEWQAGIGLILSRARKLPIATIFTTH--------ATLLGRYLC 214

  Fly   140 EVNLGMVNHAICVSHIGKENTVLRARVAKHRVSVIPNAVDTA-LFTPDPQQRPSNDIINIVVASR 203
            ..|:...|| :...:|.||   ...|...||..:...:|..| :||...:       |..:.|..
Human   215 AANIDFYNH-LDKFNIDKE---AGERQIYHRYCMERASVHCAHVFTTVSE-------ITAIEAEH 268

  Fly   204 LVYRKGIDLLAGIIPRFKNTPN-INFIIVGDGPKRDLLEEIREKTNMQERVQMVGAVEHNRVRDF 267
            ::.||. |::         ||| :|.                :|.:.....|.:.|:...|::||
Human   269 MLKRKP-DVV---------TPNGLNV----------------KKFSAVHEFQNLHAMYKARIQDF 307

  Fly   268 LVRGHIF--LNTSLTEAYCMAIV---EAASCGLQVVSTSVGGIPEVLPKSLILLAEPEIDAIYAA 327
             ||||.:  |:..|.:...:.|.   |.::.|..:...|:..:     ..|:.:.:.:|..:...
Human   308 -VRGHFYGHLDFDLEKTLFLFIAGRYEFSNKGADIFLESLSRL-----NFLLRMHKSDITVMVFF 366

  Fly   328 ILIAIDRHRKSSFKVSPSVGNGHLAS--DANGKVKRRRRRKVDTPISPTQLPAV----------- 379
            |:.|    :.::|.|....|......  |....||.:..:|:...:...::|.:
Human   367 IMPA----KTNNFNVETLKGQAVRKQLWDVAHSVKEKFGKKLYDALLRGEIPDLNDILDRDDLTI 427

  Fly   380 -----------SAPPADQNS----STEPVMCPYR 398
                       |.||...::    ||:|::...|
Human   428 MKRAIFSTQRQSLPPVTTHNMIDDSTDPILSTIR 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-A	NP_001286547.1	RfaB	1..309	CDD:223515	51/240 (21%)
		GT1_PIG-A_like	2..451	CDD:99970	70/359 (19%)
GYS2	NP_068776.2	Glycogen_syn	33..658	CDD:283373	70/359 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	628..703

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900