DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment PIG-A and Gys2

DIOPT Version :9

Sequence 1:	NP_001286547.1	Gene:	PIG-A / 37020	FlyBaseID:	FBgn0034270	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_663547.2	Gene:	Gys2 / 232493	MGIID:	2385254	Length:	704	Species:	Mus musculus

Alignment Length:	288	Identity:	53/288 - (18%)
Similarity:	101/288 - (35%)	Gaps:	66/288 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 LGLKTVFTDHSLFGFADLSAA---LTNNL------LEVNLGMVNHAICV-------SHIGKENTV 161
            |.:.||||.|:......|.||   ..|.|      .|.....:.|..|:       :|:....:.
Mouse   196 LPIATVFTTHATLLGRYLCAANIDFYNQLDKFDIDKEAGERQIYHRYCMERASVHCAHVFTTVSE 260

  Fly   162 LRARVAKHRVS-----VIPNAVDTALFTPDPQ--------QRPSNDIIN---------------- 197
            :.|..|:|.:.     |.||.::...|:...:        :....|.:.
Mouse   261 ITAIEAEHMLKRKPDVVTPNGLNVKKFSAVHEFQNLHAMYKARIQDFVRGHFYGHLDFDLEKTLF 325

  Fly   198 IVVASRLVY-RKGIDLLAGIIPRFK-----NTPNINFIIVGDGPKR------DLLEEIREKTNMQ 250
            :.:|.|..: .||.|:....:.|..     :..|:..::....|.:      :.|:....:..:.
Mouse   326 LFIAGRYEFSNKGADIFLESLSRLNFLLRMHKSNVTVVVFFIMPAKTNNFNVETLKGQAVRKQLW 390

  Fly   251 ERVQMVGAVEHNRVRDFLVRGHIFLNTSLTEAYCMAIVEAASCGLQVVSTSVGGIPEVLPKSLIL 315
            :.|..:......::.|.|:||.|....|:.:...:.|::.|     :.||....:|.|...::|
Mouse   391 DTVHCLKEKFGKKLYDGLLRGEIPDMNSILDRDDLTIMKRA-----IFSTQRQSLPPVTTHNMI- 449

  Fly   316 LAEPEIDAIYAAI-LIAIDRHRKSSFKV 342
              :...|.|.:.| .|.:..:|....||
Mouse   450 --DDSTDPILSTIRRIGLFNNRADRVKV 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIG-A	NP_001286547.1	RfaB	1..309	CDD:223515	44/252 (17%)
PIG-A	NP_001286547.1	GT1_PIG-A_like	2..451	CDD:99970	53/288 (18%)
Gys2	NP_663547.2	GT1_Glycogen_synthase_GSY2_like	27..615	CDD:99967	53/288 (18%)
		Glycogen_syn	32..657	CDD:283373	53/288 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	620..704
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900