Protein Alignment PIG-A and PIG-A

DIOPT Version :10

• Sequence 1: NP_611257.1
• Gene: PIG-A / 37020
• FlyBaseID: FBgn0034270
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: XP_309373.4
• Gene: PIG-A / 1270657
• VectorBaseID: AGAMI1_011006
• Length: 482
• Species: Anopheles gambiae
• Alignment Length: 492
• Identity: 271/492 - (55%)
• Similarity: 352/492 - (71%)
• Gaps: 41/492 - (8%)

  Fly     1 MRICMVSDFFYPSIGGVEEHVYNLSQMLLSLGHKIVVLTHAYGDCSGIRYVTGYLKVYYLPIKVC 65
            |:|||.||||||::||||||::||||.||:.||.::|:||:|||..||||:|..|||||:||||.
Mosquito     1 MKICMASDFFYPNMGGVEEHIFNLSQCLLARGHNVIVITHSYGDRKGIRYMTNGLKVYYVPIKVF 65

  Fly    66 YNQCILPTAVCNVPMLRAVLLRERVEVVHGHSAFSALAHEALMVGSLLGLKTVFTDHSLFGFADL 130
            |||.:|||.:||:|:||.:||||::::||||||||.||||.:.|..||||::|||||||||||||
Mosquito    66 YNQVVLPTMICNIPLLRYILLREQIDIVHGHSAFSTLAHETMNVAQLLGLRSVFTDHSLFGFADL 130

  Fly   131 SAALTNNLLEVNLGMVNHAICVSHIGKENTVLRARVAKHRVSVIPNAVDTALFTPDPQQRPSND- 194
            ||.:||..||::|...||.:||||.|||||||||:|.:.:|||||||||||.|||:|.:||::|
Mosquito   131 SAVVTNKFLEISLANCNHCVCVSHTGKENTVLRAKVHQDKVSVIPNAVDTAYFTPNPCRRPNDDE 195

  Fly   195 IINIVVASRLVYRKGIDLLAGIIPRFKNTPNINFIIVGDGPKRDLLEEIREKTNMQERVQMVGAV 259
            .|||||.||||||||:||||||:|:.|:.|:::|||.||||||.|||||||:.|||:||.|:||:
Mosquito   196 TINIVVVSRLVYRKGVDLLAGILPKLKHLPHVHFIIGGDGPKRALLEEIRERNNMQDRVVMLGAL 260

  Fly   260 EHNRVRDFLVRGHIFLNTSLTEAYCMAIVEAASCGLQVVSTSVGGIPEVLPKSLILLAEPEIDAI 324
            ||.:|||.||:|||||||||||||||||||||:||||||||.|||||||||.|||:|.||.:|::
Mosquito   261 EHAKVRDVLVQGHIFLNTSLTEAYCMAIVEAAACGLQVVSTKVGGIPEVLPASLIILTEPTVDSV 325

  Fly   325 YAAILIAIDRHRKSSFKVSPSVGNGHLASDANGKVKRRRRRKVDTPISPTQLPAVSAPPADQNSS 389
            |..:..||.|..:.....|....||.:  ||               ::||        |::.:.:
Mosquito   326 YRGLREAIRREMEKKQITSARYANGSI--DA---------------LAPT--------PSETSYA 365

  Fly   390 TEPVMCPYRCNELVETLYNWEDVALRTVKVYDRVLNERSFTTSELVFAVWQHGSW-FLVFFVVAH 453
            .   :|.:..|::|..||||.:|..||.|||...|.|...|...::..|.:.|.| |::...:.|
Mosquito   366 G---LCAFERNQIVANLYNWNNVTERTEKVYRTALREAPATLESMMKNVLKSGVWPFVLVIALCH 427

  Fly   454 FLMRLLELWRPRKHVEIAQDV-----------QRRAS 479
            .::|.|:.:.||||:::....           |||:|
Mosquito   428 LILRFLDWFVPRKHIDLCHSENPFLSPDCKRHQRRSS 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIG-A	NP_611257.1	GT4_PIG-A-like	2..451	CDD:340827	259/450 (58%)
PIG-A	XP_309373.4	None