Protein Alignment Hyccin and Hycc1

DIOPT Version :10

• Sequence 1: NP_611256.1
• Gene: Hyccin / 37019
• FlyBaseID: FBgn0034269
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_444320.2
• Gene: Hycc1 / 84652
• MGIID: 2149839
• Length: 521
• Species: Mus musculus
• Alignment Length: 539
• Identity: 148/539 - (27%)
• Similarity: 258/539 - (47%)
• Gaps: 89/539 - (16%)

  Fly     4 LVRDWLADYQRIRGQPSEAEAFVVEHETD----PEIAEAIFTIFNERQRNETLVHDICQQLLAFY 64
            :|.:||::::.:      .|..:..:.|:    ..:..:::.:..|.|  ..|:..:|.||..||
Mouse     8 VVEEWLSEFKTL------PETSLPNYATNLKDKSSLVTSLYKVIQEPQ--SELLEPVCHQLFEFY 64

  Fly    65 RSPEQTLHKFPLQFIPVLLYTYLHSVAGGDKKAARGVETLLICIYNGEVSTEDGGQKVVAFRMPI 129
            ||.|:.|.:|.|||:|.|::.||...|..|..::..:|.||:.:||.|:..:.|..||::|.:|.
Mouse    65 RSGEEQLLRFTLQFLPELMWCYLAVSASRDVHSSGCIEALLLGVYNLEIVDKHGHSKVLSFTIPS 129

  Fly   130 LAQTSVYHE---VKNLPMTDLRRWEENCNREVKWGPHQRIESIHAQNRMRILTALLFCYNQQVSQ 191
            |::.|||||   :.::.:|:....:...::.|..|||.:.|.:.||||..:||.||.|||..::.
Mouse   130 LSKPSVYHEPSSIGSMALTESALSQHGLSKVVYSGPHPQREMLTAQNRFEVLTFLLLCYNAALTY 194

  Fly   192 TQKSSLLHLCRVTSQLVNQGFTTKSGHGHRMSYGSDPATGVPFPKPSSPRIPLSAAFLIELVHAI 256
            ....||..||::.|::...|:..:....:|         ||      |.|||:|:.|:::::..:
Mouse   195 MPSVSLQSLCQICSRICVCGYPRQHVRKYR---------GV------SSRIPISSGFMVQMLTGV 244

  Fly   257 YFAMFNGFGTIAIQTLDDIHNRAIYEMYSEVILVTSAVRNSLHANPSGQPNDGPMGLSVALTPST 321
            |||::||...:|.:.||||..||..|:|.|.:||.:|::.||.........:|...:.|.:||:
Mouse   245 YFAIYNGEWDLAQKALDDIIYRAQLELYPEPLLVANAIKASLPHGAMKSSKEGTRCIQVEITPT- 308

  Fly   322 TTVTTSVSKSMITNASF---RTKKLPDDIPIQVQDLTIQQAPQQLASVTEETEPGTKESPSTKES 383
               ::.:|::.:|:.|.   |.|:..|      .:||.|   ::|..:||..|.....:.|:...
Mouse   309 ---SSRISRNAVTSMSIRGHRWKRHGD------TELTGQ---EELMDITEVDEGFYSRAASSTSQ 361

  Fly   384 SGTRTSIMRPSMEGIKAQAHKALIAGFKKSKDKEKEKDKEPPKPPQRKFDKHTQRNSLLQLQAEP 448
            ||...|....|.:....:..:.  :|..|:..||:|...|..:       .|..|.   |.|...
Mouse   362 SGLSNSSHNCSNKTSVGKNQRR--SGGSKAGAKERETAGESCR-------DHFARK---QTQRAQ 414

  Fly   449 SSNSSAEQPPTGEVLPLQTLSLINENGSNSFSVDSDLNDGVLGVSANTSLPPLSSTTNSVTSSDL 513
            |.|.        |:|.|:.|:|                      :::.|||..||...:.|::.:
Mouse   415 SENL--------ELLSLKRLTL----------------------TSSQSLPKPSSQGLAKTAATV 449

  Fly   514 ITKSFDSSIELAPIGHSSS 532
            .:|||: .:..||:..|.|
Mouse   450 FSKSFE-QVSGAPVPRSPS 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hyccin	NP_611256.1	Hyccin	20..346	CDD:462903	102/335 (30%)
Hycc1	NP_444320.2	Hyccin	22..330	CDD:462903	101/328 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	355..413		15/69 (22%)