Protein Alignment Hyccin and Hycc2

DIOPT Version :10

• Sequence 1: NP_611256.1
• Gene: Hyccin / 37019
• FlyBaseID: FBgn0034269
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: NP_001297527.1
• Gene: Hycc2 / 213056
• MGIID: 1098784
• Length: 586
• Species: Mus musculus
• Alignment Length: 607
• Identity: 161/607 - (26%)
• Similarity: 274/607 - (45%)
• Gaps: 117/607 - (19%)

  Fly     4 LVRDWLADYQRIRGQPSEAEAFVVEHETDPEIAEAIFTIFNERQRNETLVHDICQQLLAFYRSPE 68
            :|.:||::::.:  ..::..::.........:..|::.:..:  .|..|:..:|.||...|||.|
Mouse     8 VVEEWLSEFKAL--PDTQITSYAATLHRKKALVPALYKVIQD--SNNELLEPVCHQLFELYRSSE 68

  Fly    69 QTLHKFPLQFIPVLLYTYLHSVAGGDKKAARGVETLLICIYNGEVSTEDGGQKVVAFRMPILAQT 133
            ..|.:|.|||:|.|::.||......|:::...:|.||:.|||.|::.:||..||::|.:|.|::.
Mouse    69 VRLKRFTLQFLPELIWVYLRLTVSRDRQSNGCIEALLLGIYNLEIADKDGNNKVLSFTIPSLSKP 133

  Fly   134 SVYHE---VKNLPMTDLRRWEENCNREVKWGPHQRIESIHAQNRMRILTALLFCYNQQVSQTQKS 195
            |:|||   :.::.:|:....:.:..|.|....|.:.|:..||||..:|:.|:.|||..:.....|
Mouse   134 SIYHEPSTIGSMALTEGALCQHDLIRVVYSDLHPQRETFTAQNRFEVLSFLMLCYNSAIVYMPAS 198

  Fly   196 SLLHLCRVTSQLVNQGFTTKSGHGHRMSYGSDPATGVPFPKPSSPRIPLSAAFLIELVHAIYFAM 260
            |...|||:.|::...||..:    |...:           |....||.|...|:::|:..:|:||
Mouse   199 SYQSLCRMGSRVCVSGFPRQ----HEKQW-----------KELCGRIVLDPEFMVQLLTGVYYAM 248

  Fly   261 FNGFGTIAIQTLDDIHNRAIYEMYSEVILVTSAVRNSLHANPSGQPNDGPMGLSVALTPSTTTVT 325
            :||...:..:.||||..||..|::|:.:||.:|::|||..:......:|...|.|.:||:    .
Mouse   249 YNGQWDLGQEVLDDIIYRAQLELFSQPLLVANAMKNSLPFDAPDSSQEGQKVLKVEVTPT----V 309

  Fly   326 TSVSKSMITNASFR------------TKKLPDDIP---------------IQVQDLTIQQAPQ-- 361
            ..:|::.||.||.|            :.:....||               :|..::.:::.|:
Mouse   310 PRISRTAITTASIRRHRWRREDGFDFSNEADSSIPGSPIQHGSTDLGIKRVQEGEVLVRRTPEHG 374

  Fly   362 -----QLASVTEETE--PGTKESPSTKE-----SSGTRTSIM----RPSMEGIKAQAHKALIAGF 410
                 ..|:.||..|  .|.:||.:..:     |||...|..    :|.....:....|  :|..
Mouse   375 SPEPTSAAATTEGAEGLNGGEESLNMNDADEGFSSGASLSSQPHGTKPPSSSQRGSLRK--VATG 437

  Fly   411 KKSKDKEKE---KDKEPPKPPQRKFDKHTQRNSL-----LQLQAEPSSNSSAEQP-------PTG 460
            :.:||||..   |..|.|            |:|:     :|.||:.|.:|....|       |.|
Mouse   438 RSAKDKETALAIKSNESP------------RDSVVGKQFVQQQADLSIDSVELTPMKKHLSLPAG 490

  Fly   461 EVLP-LQTLSLI---NENGSNSFSVDSDLNDGVLGVSANTSLPPLSSTTNSVTSSDLITKSFDSS 521
            :|:| ..:||||   :.:.|.||       |.|.|..|:||   :...|..||:......:..|:
Mouse   491 QVVPKTNSLSLIRTASASSSKSF-------DYVNGGQASTS---IGVGTEGVTNLAATNANRYST 545

  Fly   522 IELAP--IGHSSSNGGKLAEHG 541
            |.|..  :|| :..|.:|...|
Mouse   546 ISLQEDRLGH-AGEGKELLSPG 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hyccin	NP_611256.1	Hyccin	20..346	CDD:462903	97/340 (29%)
Hycc2	NP_001297527.1	Hyccin	22..330	CDD:462903	97/328 (30%)