Protein Alignment Hyccin and Hyccin

DIOPT Version :10

• Sequence 1: NP_611256.1
• Gene: Hyccin / 37019
• FlyBaseID: FBgn0034269
• Length: 544
• Species: Drosophila melanogaster
• Sequence 2: XP_061507540.1
• Gene: Hyccin / 1269808
• VectorBaseID: AGAMI1_005143
• Length: 848
• Species: Anopheles gambiae
• Alignment Length: 644
• Identity: 268/644 - (41%)
• Similarity: 355/644 - (55%)
• Gaps: 130/644 - (20%)

  Fly     1 MAE-LVRDWLADYQRIRGQPSEAEAFVVEHETDPEIAEAIFTIFNERQRNETLVHDICQQLLAFY 64
            ||| ::.||::||..:  |.||...|..:||.|.||::|::||.|||.:.:.|:|.||.||..||
Mosquito     1 MAEAIIADWISDYSSL--QESELRTFAAQHENDFEISKALYTILNERTKYKDLIHPICNQLCNFY 63

  Fly    65 RSPEQTLHKFPLQFIPVLLYTYLHSVAGGDKKAARGVETLLICIYNGEVSTEDGGQKVVAFRMPI 129
            ||.|..|.:|.|||:|:|:|.||:|||.||||..|.:|||||||||.|||::||..|||:||||:
Mosquito    64 RSNEAELRRFTLQFVPMLIYLYLNSVALGDKKGCRSIETLLICIYNIEVSSDDGSPKVVSFRMPV 128

  Fly   130 LAQTSVYHEVKNLPMTDLRRWEENCNREVKWGPHQRIESIHAQNRMRILTALLFCYNQQVSQTQK 194
            |||||||||.|:|..:||||||||.|:::.|||...||||:||||::::|||||.||||::|..|
Mosquito   129 LAQTSVYHEEKSLQPSDLRRWEENSNKDINWGPLPSIESINAQNRLKVMTALLFTYNQQLNQIHK 193

  Fly   195 SSLLHLCRVTSQLVNQGF-TTKSGHGHRMSYGSDPAT---GVPFPKPS-----SPRIPLSAAFLI 250
            .:|.|||:.||.|||||| ....||.||.|||:||.:   .:....||     .|||.:::.||:
Mosquito   194 PALYHLCKTTSLLVNQGFPKLPGGHMHRSSYGNDPISPQQPMAMAAPSHVVRPPPRIAVNSQFLV 258

  Fly   251 ELVHAIYFAMFNGFGTIAIQTLDDIHNRAIYEMYSEVILVTSAVRNSLHANPSGQPNDGPMGLSV 315
            ||.||.||||||.|.:.||:.:.|:|:||.|||..||||||:|:||||||||||||:|||||:||
Mosquito   259 ELAHANYFAMFNEFASAAIEAVTDLHSRACYEMLPEVILVTNAIRNSLHANPSGQPSDGPMGISV 323

  Fly   316 ALTPSTTTVTTSVSKSMITNASFRTKKLPDDIPIQVQDL---TIQQAPQQLASVTEE-------- 369
            ||||:|||||  |||||||||||||||||||:.::..:.   |.|:...:||.:..:
Mosquito   324 ALTPATTTVT--VSKSMITNASFRTKKLPDDLEVEFVNALQSTQQEMMSKLAMIDADVGNDAGGA 386

  Fly   370 --------------------------TEPGTKESPST----KESS-------------------- 384
                                      .:|.| .||.|    ||||
Mosquito   387 GTAVCSAAGGGGTGTQIAVNIGPDGTVDPDT-NSPRTETKKKESSRKWKNWGWKTNAPTGAAANA 450

  Fly   385 ------GTR-TSIMR----PSMEG--------IKAQAHKALIAGFKKSKDKEKEKDKEPPKPPQR 430
                  ||: |||..    |...|        ..:..|| |:.|..|.:|........|....::
Mosquito   451 NGTGAGGTKQTSIEEEADSPKRSGGSTRHSSPADSPKHK-LLLGTGKVEDVNSNASVSPASLRRK 514

  Fly   431 KFDKHTQRNSLLQLQAEPSS--------NSSAEQPPTGEVLPL------QTLSLI---------- 471
            ||.....::.:.:.:|..|:        .||.:...:.|:..|      .|:.||
Mosquito   515 KFLSSKNQSPVNRSEARASAGARLYEEFESSLQDSDSDELAALIVNGRPATIHLIQPSTIPDDIP 579

  Fly   472 ------NENGS----NSFSVDSDLNDGVLGVSANTSLPPLSSTTNSVTSSDLITKSFDS 520
                  .|||:    :..|::.|...|:.....:|......:.|.|.|:|....|..||
Mosquito   580 IQGPTKEENGAPGHQHLTSINEDCESGLPSTDGSTKGTIAGAGTGSSTASGTPGKPKDS 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hyccin	NP_611256.1	Hyccin	20..346	CDD:462903	206/334 (62%)
Hyccin	XP_061507540.1	None