Protein Alignment CG34195 and METTL8

DIOPT Version :9

• Sequence 1: NP_001097360.1
• Gene: CG34195 / 37018
• FlyBaseID: FBgn0085224
• Length: 283
• Species: Drosophila melanogaster
• Sequence 2: XP_016860473.1
• Gene: METTL8 / 79828
• HGNCID: 25856
• Length: 468
• Species: Homo sapiens
• Alignment Length: 380
• Identity: 121/380 - (31%)
• Similarity: 173/380 - (45%)
• Gaps: 110/380 - (28%)

  Fly     3 PLEPDVITTQA--------------KELSAVERQKLDEQNKRGLVPEYKANKLEIDAQRNWDIFY 53
            ||...::|..|              ||..|..|:|:.|.:...::.|.:. |.|.:|.:.||.||
Human    78 PLGSRILTDPAKVFEHNMWDHMQWSKEEEAAARKKVKENSAVRVLLEEQV-KYEREASKYWDTFY 141

  Fly    54 KRNETRFFKDRHWTTREFQELL-----------------------------------DQEEFHEK 83
            |.::.:|||||:|..|||.|:|                                   |::..:||
Human   142 KIHKNKFFKDRNWLLREFPEILPVDQKPEEKARESSWDHVKTSATNRFSRMHCPTVPDEKNHYEK 206

  Fly    84 RT---------------------------------------LFEVGCGVGNLVFPLLEE-QTSEE 108
            .:                                       :.|||||.||.|||:|.. :.|.|
Human   207 SSGSSEGQSKTESDFSNLDSEKHKKGPMETGLFPGSNATFRILEVGCGAGNSVFPILNTLENSPE 271

  Fly   109 GCFSNSRFFFYACDFSPRAVEFV-------------RSNPLYDPSQISAFQCDITTQQVHDHIPP 160
            .       |.|.|||:..|||.|             :|:..|..:|..||..|:....:....|.
Human   272 S-------FLYCCDFASGAVELVKVCYSWESYQLMPKSHSSYRATQCFAFVHDVCDDGLPYPFPD 329

  Fly   161 SSVDICTLIFVLSAIHPQKFKDVVQNLGKLLKPGGLLLFRDYGLYDMAQLRFKPGNKIAENLYVR 225
            ..:|:..|:||||:|||.:.:.||..|.|||||||:|||||||.||..|||||.|:.::||.|||
Human   330 GILDVILLVFVLSSIHPDRMQGVVNRLSKLLKPGGMLLFRDYGRYDKTQLRFKKGHCLSENFYVR 394

  Fly   226 QDGTRSYFFSEEEVSKLFQENGFEVITNAYVHRRTLNLKEGVDVPRIFLQGKFRR 280
            .||||:|||::.||..:|.:...:...|....|..:|.|:.|.:.|:::||||::
Human   395 GDGTRAYFFTKGEVHSMFCKASLDEKQNLVDRRLQVNRKKQVKMHRVWIQGKFQK 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34195	NP_001097360.1	Methyltransf_12	88..>175	CDD:369778	35/100 (35%)
METTL8	XP_016860473.1	Methyltransf_25	248..364	CDD:379312	46/122 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2361
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D378076at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820