DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG34195 and mettl6

DIOPT Version :9

Sequence 1:	NP_001097360.1	Gene:	CG34195 / 37018	FlyBaseID:	FBgn0085224	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_956497.2	Gene:	mettl6 / 791999	ZFINID:	ZDB-GENE-040426-926	Length:	286	Species:	Danio rerio

Alignment Length:	276	Identity:	154/276 - (55%)
Similarity:	190/276 - (68%)	Gaps:	12/276 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 PDVITTQAKELSAVERQKLDEQNKRGLVPEYKANKLEIDAQRNWDIFYKRNETRFFKDRHWTTRE 70
            |.....:.:.|:..|.:||.  |.|.||.::|..|||.|||:|||:|||||.|.|||||||||||
Zfish    18 PQSTVVRERSLTPEEMEKLG--NDRVLVSDFKQQKLETDAQKNWDLFYKRNTTNFFKDRHWTTRE 80

  Fly    71 FQELLD-QEEFHEKRTLFEVGCGVGNLVFPLLEEQTSEEGCFSNSRFFFYACDFSPRAVEFVRSN 134
            |.||.: :|...:|..|.|.||||||.:||||||..:         .|.|||||||||||||:.|
Zfish    81 FDELKNCRESEGQKLVLLEAGCGVGNCIFPLLEEDLN---------IFIYACDFSPRAVEFVKKN 136

  Fly   135 PLYDPSQISAFQCDITTQQVHDHIPPSSVDICTLIFVLSAIHPQKFKDVVQNLGKLLKPGGLLLF 199
            .||...:..|||||:|...:..:|...:||:.|||||||||||.|.:..::.:.|:|:|||::.|
Zfish   137 ALYCTERCLAFQCDLTKDDLQANIQVGTVDVATLIFVLSAIHPDKMQKSLEQIYKVLRPGGIVFF 201

  Fly   200 RDYGLYDMAQLRFKPGNKIAENLYVRQDGTRSYFFSEEEVSKLFQENGFEVITNAYVHRRTLNLK 264
            |||||||.|.||||.|||:.||.|||||||||:|||.|.::.|||..|||.:.|.||.|.|:|.|
Zfish   202 RDYGLYDHAMLRFKSGNKLGENFYVRQDGTRSFFFSREYLAGLFQNAGFETLVNEYVLRETVNKK 266

  Fly   265 EGVDVPRIFLQGKFRR 280
            ||:.|||:|||.||||
Zfish   267 EGLCVPRVFLQSKFRR 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34195	NP_001097360.1	Methyltransf_12	88..>175	CDD:369778	46/86 (53%)
mettl6	NP_956497.2	SmtA	71..261	CDD:223574	112/198 (57%)
		Methyltransf_12	98..199	CDD:285454	56/109 (51%)
		AdoMet_MTases	<164..250	CDD:302624	53/85 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596516
Domainoid	1	1.000	76	1.000	Domainoid score	I8974
eggNOG	1	0.900	-	-		E1_KOG2361
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12069
Inparanoid	1	1.050	306	1.000	Inparanoid score	I2615
OMA	1	1.010	-	-		QHG51971
OrthoDB	1	1.010	-	-		D378076at33208
OrthoFinder	1	1.000	-	-		FOG0000942
OrthoInspector	1	1.000	-	-		oto41772
orthoMCL	1	0.900	-	-		OOG6_104549
Panther	1	1.100	-	-	LDO	PTHR22809
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1971
SonicParanoid	1	1.000	-	-		X3769
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800