DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34195 and Mettl2

DIOPT Version :9

Sequence 1:	NP_001097360.1	Gene:	CG34195 / 37018	FlyBaseID:	FBgn0085224	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_766155.3	Gene:	Mettl2 / 52686	MGIID:	1289171	Length:	389	Species:	Mus musculus

Alignment Length:	330	Identity:	116/330 - (35%)
Similarity:	163/330 - (49%)	Gaps:	70/330 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 AKELSAVERQKLDEQNKRGLVPEYKANKLEIDAQRNWDIFYKRNETRFFKDRHWTTREFQEL--- 74
            ::|.:|...:|:.|.:...:.|| |....|::|.:.||.||:.:|..|||||||...||.||
Mouse    43 SEEQAAAAERKVQENSSPLVCPE-KQVDYEVNAHKYWDDFYRIHENGFFKDRHWLFTEFPELAPS 106

  Fly    75 --------------------------------------------------------LDQEEFHEK 83
                                                                    :..|||...
Mouse   107 HSHLTGVPLEKQRSDVCEDGPGLTAEQHKCSCASPGCETQVPPLEEPVTQKLGHLEISGEEFPGS 171

  Fly    84 RT---LFEVGCGVGNLVFPLLEEQTSEEGCFSNSRFFFYACDFSPRAVEFVRSNPLYDPSQISAF 145
            ..   :.||||||||.|||:|  ||:     :|...|.|.||||..|:|.:::|..||||:..||
Mouse   172 SATYRILEVGCGVGNTVFPIL--QTN-----NNPNLFVYCCDFSATAIELLKTNSQYDPSRCYAF 229

  Fly   146 QCDITTQQVHDHIPPSSVDICTLIFVLSAIHPQKFKDVVQNLGKLLKPGGLLLFRDYGLYDMAQL 210
            ..|:..:.....:|..|:|:..||||||||.|.|.:..:..|.:||||||::|.||||.||||||
Mouse   230 VHDLCDEDQSYPVPEDSLDVIVLIFVLSAIVPDKMQKAISKLSRLLKPGGVMLLRDYGRYDMAQL 294

  Fly   211 RFKPGNKIAENLYVRQDGTRSYFFSEEEVSKLFQENGFEVITNAYVHRRTLNLKEGVDVPRIFLQ 275
            |||.|..::.|.|||.||||.|||::.|:..||...|.|.:.|....|..:|..:.:.:.|:::|
Mouse   295 RFKKGQCLSGNFYVRGDGTRVYFFTQGELDTLFTAAGLEKVQNLVDRRLQVNRGKQLTMYRVWIQ 359

  Fly   276 GKFRR 280
            .|:.:
Mouse   360 CKYSK 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34195	NP_001097360.1	Methyltransf_12	88..>175	CDD:369778	40/86 (47%)
Mettl2	NP_766155.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
Mettl2	NP_766155.3	Methyltransf_12	178..280	CDD:369778	50/108 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2361
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D378076at33208
OrthoFinder	1	1.000	-	-		FOG0000942
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820