Protein Alignment CG34195 and Mettl2

DIOPT Version :10

• Sequence 1: NP_001097360.1
• Gene: CG34195 / 37018
• FlyBaseID: FBgn0085224
• Length: 283
• Species: Drosophila melanogaster
• Sequence 2: NP_001102309.1
• Gene: Mettl2 / 363687
• RGDID: 1310240
• Length: 385
• Species: Rattus norvegicus
• Alignment Length: 335
• Identity: 118/335 - (35%)
• Similarity: 168/335 - (50%)
• Gaps: 75/335 - (22%)

  Fly    13 AKELSAVERQKLDEQNKRGLVPEYKANKLEIDAQRNWDIFYKRNETRFFKDRHWTTREFQELLD- 76
            ::|.:|...:|:.|.:.:.:.||.:|: .|::|.:.||.|||.:|..|||||||...||.||..
  Rat    43 SEEQAAAAERKVQENSSQLVCPEKQAD-YEVNAHKYWDDFYKVHENGFFKDRHWLFTEFPELAPS 106

  Fly    77 -------------------------------------------------QEEFHEKRT------- 85
                                                             :|...:|.|
  Rat   107 HDHLVNLHLEKQKNEVSKPRSSEDGPGLAAEQHKRPCTSHGCETRVPPVEEPVTQKLTHLEICAD 171

  Fly    86 ----------LFEVGCGVGNLVFPLLEEQTSEEGCFSNSRFFFYACDFSPRAVEFVRSNPLYDPS 140
                      :.||||||||.|||:|  ||:     :|...|.|.||||..|:|.|::|..||||
  Rat   172 DFPGSSATYRILEVGCGVGNTVFPIL--QTN-----NNPDLFVYCCDFSATAIELVKTNSEYDPS 229

  Fly   141 QISAFQCDITTQQVHDHIPPSSVDICTLIFVLSAIHPQKFKDVVQNLGKLLKPGGLLLFRDYGLY 205
            :..||..|:..:.....:|..|:|:..||||||||.|.|.:..:..|.:||||||::|.||||.|
  Rat   230 RCFAFVHDLCDEDQSYPMPKDSLDVIVLIFVLSAIVPDKMQKAISKLSRLLKPGGVMLLRDYGRY 294

  Fly   206 DMAQLRFKPGNKIAENLYVRQDGTRSYFFSEEEVSKLFQENGFEVITNAYVHRRTLNLKEGVDVP 270
            ||||||||.|..::.|.|||.||||.|||:::|:..||...|.|.:.|....|..:|..:.:.:.
  Rat   295 DMAQLRFKKGQCLSGNFYVRGDGTRVYFFTQDELDTLFTAAGLEKVQNVVDRRLQVNRGKQLTMY 359

  Fly   271 RIFLQGKFRR 280
            |:::|.|:.:
  Rat   360 RVWIQCKYSK 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34195	NP_001097360.1	Methyltransf_12	87..>175	CDD:400515	41/87 (47%)
Mettl2	NP_001102309.1	Methyltransf_25	182..284	CDD:463945	50/108 (46%)