DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG34195 and mettl2a

DIOPT Version :9

Sequence 1:	NP_001097360.1	Gene:	CG34195 / 37018	FlyBaseID:	FBgn0085224	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001017902.1	Gene:	mettl2a / 100006618	ZFINID:	ZDB-GENE-050417-462	Length:	353	Species:	Danio rerio

Alignment Length:	300	Identity:	120/300 - (40%)
Similarity:	167/300 - (55%)	Gaps:	42/300 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ELSAVERQ---KLDEQNKRGLVPEYKANKLEIDAQRNWDIFYKRNETRFFKDRHWTTREFQELLD 76
            |.||.:.:   |..::|.:.| |..|..:.:..|...|:.||..:|.||||||||...||.||..
Zfish    57 EWSAEQEEAALKKVQENSQPL-PAEKQEEFDNRANEYWNDFYTIHENRFFKDRHWLFTEFPELAP 120

  Fly    77 QEEF----HEKRTL---------------------------FEVGCGVGNLVFPLLEEQTSEEGC 110
            |::.    .||.:|                           .||||||||.|||:|:..
Zfish   121 QQKHLRGAEEKESLEHMLNGEDISLNPTHDEFPGASASYRILEVGCGVGNTVFPILKTN------ 179

  Fly   111 FSNSRFFFYACDFSPRAVEFVRSNPLYDPSQISAFQCDITTQQVHDHIPPSSVDICTLIFVLSAI 175
             ::...|.|.||||..||:.|:|||.||||:..||..|::.:.....:|..|:|:..|||||||:
Zfish   180 -NDPGLFVYCCDFSSTAVDLVKSNPEYDPSRCHAFVHDMSDESGEYPMPDHSLDVIVLIFVLSAL 243

  Fly   176 HPQKFKDVVQNLGKLLKPGGLLLFRDYGLYDMAQLRFKPGNKIAENLYVRQDGTRSYFFSEEEVS 240
            ||:|.:..:..||:||||||:||.||||.|||||||||.|..::||.|||.|||..|||:::|:.
Zfish   244 HPEKMQKSINRLGRLLKPGGVLLLRDYGRYDMAQLRFKKGRCLSENFYVRGDGTLVYFFTQDELH 308

  Fly   241 KLFQENGFEVITNAYVHRRTLNLKEGVDVPRIFLQGKFRR 280
            .||...|.|.:.|....|..:|..:.:.:.|:::|.|:|:
Zfish   309 DLFSSAGLEKLQNLADRRLQVNRGKQLTMYRVWVQCKYRK 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG34195	NP_001097360.1	Methyltransf_12	88..>175	CDD:369778	40/86 (47%)
mettl2a	NP_001017902.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
mettl2a	NP_001017902.1	Methyltransf_25	161..263	CDD:379312	50/108 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	173	1.000	Domainoid score	I3661
eggNOG	1	0.900	-	-		E1_KOG2361
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D378076at33208
OrthoFinder	1	1.000	-	-		FOG0000942
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820