DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx16 and Snx29

DIOPT Version :9

Sequence 1:	NP_611252.1	Gene:	Snx16 / 37015	FlyBaseID:	FBgn0034265	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_006522729.1	Gene:	Snx29 / 74478	MGIID:	1921728	Length:	819	Species:	Mus musculus

Alignment Length:	379	Identity:	94/379 - (24%)
Similarity:	147/379 - (38%)	Gaps:	106/379 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 ETGTGYGNNNNHLAAP--ARTSQATLFKKASTAITSPKKSLLKTGN-------------SVCGLD 59
            |.|||   ..||:...  .|.|:    :.:|....||..|||.:.:             .|..::
Mouse   425 ENGTG---TENHIIPEPGLRYSR----EASSPGQGSPLSSLLPSASVPESMTVHELRQAIVAMMN 482

  Fly    60 KRSQFREQ-----KLLGRKCHSSPDLRQ----------------IGKYQ----NNSLLR------ 93
            ::.:..|:     .||..:...|..|||                ..|.|    .|.:|:
Mouse   483 RKDELEEENGSLRNLLDGEMEHSAALRQEVDALRRKVTEQQERHATKVQALARENEVLKVQLKKY 547

  Fly    94 ------SKSEGDVSLILAS--NSGAPLTVANAKSEVCLQRISSHSYEQSPRTPINKSEMLG---- 146
                  .|.||..:..:.|  |..|.:||...|.....:.::| |||   |..|..:||.|
Mouse   548 VGAVQMLKREGQTAEAVPSLWNVDAEVTVPEQKPGEVAEELAS-SYE---RKLIEVAEMHGELIE 608

  Fly   147 -GARSHRDL-TQSSYGNQAGGHSVDLESRSRTPRRMSECSLGYSQSSSRHTGSNSMFASQMTLSS 209
             ..|.||.| .:.:..:|.....:||  |...|..:|:.|...|             .|...:|:
Mouse   609 FNERLHRALVAKEALVSQMRQELIDL--RGPVPGDLSQTSEDQS-------------LSDFEISN 658

  Fly   210 GSVVPPVDPNAVLRVPIIGYEVMEERARFTAYK--LRVENPETNDYWLVMRRYTDFVRLNSKLKQ 272
            .:::....|:..||        .:....|..|:  :|::    :|.|.|.||||:|..|:.:|:.
Mouse   659 RALINVWIPSVFLR--------GKAANAFHVYQVYIRIK----DDEWNVYRRYTEFRALHHQLQS 711

  Fly   273 AFPNL-TLMLPRKKLFGDNFNAVFLDNRVQGLQIFVNSVMAKEELRKCKLVREF 325
            |||.: ....|.||..| |.:|.|::.|.:.||.::.|||.|    ..::|.||
Mouse   712 AFPQVRAYSFPPKKAIG-NKDAKFVEERRKQLQSYLRSVMNK----VIQMVPEF 760

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx16	NP_611252.1	PX_SNX16	219..329	CDD:132809	35/110 (32%)
Snx29	XP_006522729.1	RUN	44..177	CDD:367169
		Smc	<472..>634	CDD:224117	35/165 (21%)
		PX_RUN	662..779	CDD:132810	36/116 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900