DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx16 and Snx29

DIOPT Version :9

Sequence 1:	NP_611252.1	Gene:	Snx16 / 37015	FlyBaseID:	FBgn0034265	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_038942785.1	Gene:	Snx29 / 689142	RGDID:	1596162	Length:	838	Species:	Rattus norvegicus

Alignment Length:	356	Identity:	93/356 - (26%)
Similarity:	149/356 - (41%)	Gaps:	72/356 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LRKRETGT-GYGNNNNHLAAPARTSQATL---FKKASTAITSPKKSLLKTGNSVCGL-----DKR 61
            ||.||.|: |.|:..:.|...|...::..   .::|..|:.:.|..|.:...|:..|     :..
  Rat   460 LRYREAGSPGRGSPLSSLLPSASVPESMTVHELRQAIVAMMNRKDELEEENGSLRNLLDGEMEHS 524

  Fly    62 SQFREQ-KLLGRKCHSSPDLRQIGKYQ----NNSLLR------------SKSEGDVSLILAS--N 107
            :..|:: ..|.||.....: |...|.|    .|.:|:            .|.||..:.::.|  |
  Rat   525 AALRQEVDALRRKVTEQQE-RHATKVQALARENEVLKVQLKKYVGAVQMLKREGQTAEVVPSLWN 588

  Fly   108 SGAPLTVANAKSEVCLQRISSHSYEQSPRTPINKSEMLG-----GARSHRDL-TQSSYGNQAGGH 166
            ..|.:||...|.....:.::| |||   |..|..:||.|     ..|.||.| .:.:..:|....
  Rat   589 VDAEVTVPEQKPGEVAEELAS-SYE---RKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQE 649

  Fly   167 SVDLESRSRTPRRMSECSLGYSQSSSRHTGSNSMFASQMTLSSGSVVPPVDPNAVLRVPII-GYE 230
            .:||  |...|..:|:.|...|             .|...:|:.:::....|:..||.... .|.
  Rat   650 LIDL--RGPVPGDLSQTSEDQS-------------LSDFEISNRALINVWIPSVFLRGKAANAYH 699

  Fly   231 VMEERARFTAYKLRVENPETNDYWLVMRRYTDFVRLNSKLKQAFPNL-TLMLPRKKLFGDNFNAV 294
            |      :..| :|::    :|.|.|.||||:|..|:.:|:.|||.: ....|.||..| |.:|.
  Rat   700 V------YQVY-IRIK----DDEWNVYRRYTEFRGLHHQLQSAFPQVRAYSFPPKKAIG-NKDAK 752

  Fly   295 FLDNRVQGLQIFVNSVMAKEELRKCKLVREF 325
            |::.|.:.||.::.|||.|    ..::|.||
  Rat   753 FVEERRKQLQSYLRSVMNK----VIQMVPEF 779

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx16	NP_611252.1	PX_SNX16	219..329	CDD:132809	36/109 (33%)
Snx29	XP_038942785.1	RUN	64..197	CDD:397055
		COG1340	489..654	CDD:224259	40/171 (23%)
		PX_RUN	681..798	CDD:132810	37/115 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900