DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx16 and PXK

DIOPT Version :9

Sequence 1:	NP_611252.1	Gene:	Snx16 / 37015	FlyBaseID:	FBgn0034265	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001336421.1	Gene:	PXK / 54899	HGNCID:	23326	Length:	581	Species:	Homo sapiens

Alignment Length:	168	Identity:	52/168 - (30%)
Similarity:	84/168 - (50%)	Gaps:	29/168 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   224 VPI-IGYEVMEERARFTAYKLRVENP-ETNDYWLVMRRYTDFVRLNSKLKQAFPNLTLMLPRKKL 286
            ||: ...|..:.....|.|.:||:.. ...:.|.::|||:||..||:.|:.|  .|:|.||.|||
Human    18 VPLTAAIEASQSLQSHTEYIIRVQRGISVENSWQIVRRYSDFDLLNNSLQIA--GLSLPLPPKKL 80

  Fly   287 FGDNFNAVFLDNRVQGLQIFVNSVMAKEELRKCKLVREFFCLDEPPSYSE-----SMEECRAIF- 345
            .| |.:..|:..|.:|||.::|.:.....|..|:||::|.   :|.:||.     ::::....|
Human    81 IG-NMDREFIAERQKGLQNYLNVITTNHILSNCELVKKFL---DPNNYSANYTEIALQQVSMFFR 141

  Fly   346 -EAQEETIEHLK------------LQIRN--KNDLILS 368
             |.:.|.:|.||            ::|:|  |..|:||
Human   142 SEPKWEVVEPLKDIGWRIRKKYFLMKIKNQPKERLVLS 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx16	NP_611252.1	PX_SNX16	219..329	CDD:132809	37/106 (35%)
PXK	NP_001336421.1	PX_MONaKA	13..132	CDD:132781	40/119 (34%)
		SPS1	186..492	CDD:223589
		PKc	198..345	CDD:270622
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810