DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Snx16 and snz

DIOPT Version :9

Sequence 1:	NP_611252.1	Gene:	Snx16 / 37015	FlyBaseID:	FBgn0034265	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001284993.1	Gene:	snz / 31704	FlyBaseID:	FBgn0029976	Length:	1117	Species:	Drosophila melanogaster

Alignment Length:	392	Identity:	79/392 - (20%)
Similarity:	130/392 - (33%)	Gaps:	120/392 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 QFREQKLLGRKCHSSPDLRQIGKYQNNSLLRSKSEGDVSLILAS---------NSG--------A 110
            |:|:.|       .:.|..:|.   :.:||...:.|||...||.         |.|        |
  Fly   528 QYRQLK-------EALDSNEIA---DPTLLMCHTIGDVQEPLADEQPGAADGLNGGAGGAIDVAA 582

  Fly   111 PLTVANAKSEVCLQRISSHSYEQSPRTPINKSEMLGGARSHRDLTQSSYGNQAGGHSVDLESR-- 173
            ..:.|..|.|...:||.            .|::.|...:                :||..||:
  Fly   583 HTSYARRKLEQIQERID------------KKNQALDALK----------------YSVKPESKVL 619

  Fly   174 ---------SRTPRRMSECSLGYSQSSSRHTGSNSMFASQMTLSSGSVVPPVDPNAVLRVPIIGY 229
                     .::.:|.:|..|..:.:.:.|.|.     .:.|:.|   |...|....|:..|:.:
  Fly   620 TILEKEMEWLKSEKRQTEAHLRRTDAWTEHLGK-----WKATIQS---VEVSDEKESLQFMILVH 676

  Fly   230 --EVMEERARFTAYK--------LRVENPETNDYWLVMRRYTDFVRLNSKLKQAFPNL-TLMLPR 283
              |.:....:.|:.|        ||......:..|:|||.......|..||:....|| .:.||
  Fly   677 VDEDINAPVQPTSSKNGDSGHANLRKRPSGISSGWVVMRSLNQVHELQRKLRHVSSNLKAIDLP- 740

  Fly   284 KKLFGDNFNAVFLDNRVQG-------LQIFVNSVMAKEELRKCKLVREFFCLDEP------PSYS 335
                 .||...||.....|       :|.|:|.::..:.|...:.:..|......      ||..
  Fly   741 -----TNFKFFFLKTDRHGQEKAKSQIQKFLNFILEDDHLNGSEAIYTFLSPSSDHLKQSLPSPK 800

  Fly   336 ESMEECRAIF--------EAQEETIEHLKLQIRNKNDLILSLQ-------QKLREEMNEKEQLRE 385
            :|......:|        ||.:.|.....|| |:..|:...|.       :.|..:::.|:.:.|
  Fly   801 KSKFSLSTLFRSDAGKAHEASKATDPFWGLQ-RDDEDISTYLDGESGGEAKMLAADLDSKDSIAE 864

  Fly   386 AM 387
            .|
  Fly   865 PM 866

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx16	NP_611252.1	PX_SNX16	219..329	CDD:132809	28/127 (22%)
snz	NP_001284993.1	PXA	142..299	CDD:280373
		RGS_SNX25	422..531	CDD:188675	1/2 (50%)
		PX_SNX25	645..788	CDD:132788	34/156 (22%)
		Nexin_C	882..987	CDD:285792
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900