DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Snx16 and RPS6KC1

DIOPT Version :9

Sequence 1:	NP_611252.1	Gene:	Snx16 / 37015	FlyBaseID:	FBgn0034265	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_036556.2	Gene:	RPS6KC1 / 26750	HGNCID:	10439	Length:	1066	Species:	Homo sapiens

Alignment Length:	208	Identity:	50/208 - (24%)
Similarity:	81/208 - (38%)	Gaps:	44/208 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   229 YEVMEERAR---FTAYKL--RV---ENPETNDYWLVMRRYTDFVRLNSKLKQAFPNL----TLML 281
            |.|.|.:..   :|.||:  ||   .|||.....:|.:||:||.:|:.:|.|...||    .|..
Human    15 YTVTEPQRHPRGYTVYKVTARVVSRRNPEDVQEIIVWKRYSDFKKLHKELWQIHKNLFRHSELFP 79

  Fly   282 PRKK--LFGDNFNAVFLDNRVQGLQIFVNSVMAKEELRKCKLVREFF----------CLDEPPSY 334
            |..|  :|| .|:...::.|.|..:..:........|...|.:.:||          .:....::
Human    80 PFAKGIVFG-RFDETVIEERRQCAEDLLQFSANIPALYNSKQLEDFFKGGIINDSSELIGPAEAH 143

  Fly   335 SESM----EECRAIFEAQEETIEHLKLQIRNKNDLILSLQQKLREEMNEKEQLREAMKNMELNCS 395
            |:|:    .||.....:.:..:..|.:.:    |.:..|...:....|      ..::...||.|
Human   144 SDSLIDTFPECSTEGFSSDSDLVSLTVDV----DSLAELDDGMASNQN------SPIRTFGLNLS 198

  Fly   396 HCSS-----ASDS 403
            ..||     ||||
Human   199 SDSSALGAVASDS 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx16	NP_611252.1	PX_SNX16	219..329	CDD:132809	33/123 (27%)
RPS6KC1	NP_036556.2	PX_RPK118_like	11..128	CDD:132820	33/113 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	207..228		4/5 (80%)
		MIT_SNX15	238..312	CDD:239140
		PKc_like	335..>421	CDD:304357
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	441..509
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	553..596
		S_TKc	<875..1056	CDD:214567
		STKc_RPK118_like	<879..1056	CDD:270728
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810