DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Snx16 and Snx14

DIOPT Version :9

Sequence 1:	NP_611252.1	Gene:	Snx16 / 37015	FlyBaseID:	FBgn0034265	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001346887.2	Gene:	Snx14 / 244962	MGIID:	2155664	Length:	946	Species:	Mus musculus

Alignment Length:	438	Identity:	96/438 - (21%)
Similarity:	159/438 - (36%)	Gaps:	147/438 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 KKSLLKTGNSVCGLDKRSQFREQK-LLGRKCHSSPDLRQIGKYQ-----------NNSLLRSKSE 97
            |.|:||.        :..|.|||: ||.|..:.   |:|.|...           |:.:||.:..
Mouse   329 KPSVLKL--------ELKQIREQQDLLFRFMNF---LKQEGAVHVLQFCLTVEEFNDRILRPELS 382

  Fly    98 GDVSLILASN-------------------------------SGAPLTVANAKSEVCLQRISSH-- 129
            .|..|.|...                               .|..:.|...::..||.....|
Mouse   383 NDEMLSLHEELQKIYKTYCLDESIDKIRFDPFIVEEIQRIAEGPYIDVVKLQTMRCLFEAYEHVL 447

  Fly   130 SYEQSPRTPI--NKSE----MLGGARSHRDLTQSSYGNQAGGHSVDLESRSRTPRRMSECSLGYS 188
            |..::..||:  :..|    :|.||.|.   |::|..|:.   |:.|:....|.:|..  |.|.|
Mouse   448 SLLENVFTPMFCHSDEYFRQLLRGAESP---TRNSKFNRG---SLSLDDFRSTQKRGE--SFGIS 504

  Fly   189 QSSSRHTGSNSMFASQMTLSSGSVVP-----------------------PVD----PNA------ 220
            :..|:..|   :|.|  |...|:|:|                       ||:    ||.
Mouse   505 RIGSKIKG---VFKS--TTMEGAVLPNYGVAEGEDDFIEEGIVVMEDDSPVEAVSTPNTPRNLAA 564

  Fly   221 -VLRVPIIGY------EVMEERARFTAYKLRVENPETN------DYWLVMRRYTDFVRLNSKLKQ 272
             .:.:|.:.:      |..|::.|...:.:.||..:..      ::|.|.|||.:|..|.|||.:
Mouse   565 WKISIPYVDFFEDPSSERKEKKERIPVFCIDVERNDRRAVGHEPEHWSVYRRYLEFYVLESKLTE 629

  Fly   273 ---AFPNLTLMLPRKKLFGDNFNAVFLDNRVQGLQIFVNSVMAKEELRKCKLVREFFCLDEPPSY 334
               .||:  ..||.|::.|.. |..||.::.:..|.::..::...||...:|:.:|.    .|:.
Mouse   630 FHGTFPD--AQLPSKRIIGPK-NYEFLKSKREEFQEYLQKLVQHPELSNSQLLADFL----SPNG 687

  Fly   335 SESMEECRAIFEAQEETIEHLKLQIRNKNDLILSLQQKLREEMNEKEQ 382
            .|:            :.::.:...: |...:|.|:..||   |.||.|
Mouse   688 GET------------QFLDKILPDV-NLGKIIKSVPGKL---MKEKGQ 719

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx16	NP_611252.1	PX_SNX16	219..329	CDD:132809	31/131 (24%)
Snx14	NP_001346887.2	PXA	130..299	CDD:308031
		RGS_SNX14	340..466	CDD:188677	24/128 (19%)
		PX_SNX14	564..686	CDD:132787	30/128 (23%)
		Nexin_C	807..911	CDD:337134
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810