DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx16 and SGK3

DIOPT Version :9

Sequence 1:	NP_611252.1	Gene:	Snx16 / 37015	FlyBaseID:	FBgn0034265	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001028750.1	Gene:	SGK3 / 23678	HGNCID:	10812	Length:	496	Species:	Homo sapiens

Alignment Length:	134	Identity:	45/134 - (33%)
Similarity:	69/134 - (51%)	Gaps:	10/134 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   230 EVMEERARFTAYKLRVENPETNDYWLVMRRYTDFVRLNSKLKQAFPNLTLMLPRKKLFGDNFNAV 294
            |..|::.|||.||:.|....:.  |.|.|||.:|.:|.:.||:.||.:.|.:|.|::|||||:..
Human    23 EHREKKKRFTVYKVLVSVGRSE--WFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPD 85

  Fly   295 FLDNRVQGLQIFVNSVMAKEELRKCKLVREFFCLDEPPSYSESMEECRAIFEAQEETIEHLKLQI 359
            |:..|..||..|:.:::...||.....||.|..:|.|...|:..|:        |:.....||..
Human    86 FIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSED--------EDERSSQKLHS 142

  Fly   360 RNKN 363
            .::|
Human   143 TSQN 146

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx16	NP_611252.1	PX_SNX16	219..329	CDD:132809	37/98 (38%)
SGK3	NP_001028750.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		PX_CISK	12..120	CDD:132780	37/98 (38%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	121..156		7/34 (21%)
		STKc_SGK3	165..490	CDD:270755
		Nuclear localization signal. /evidence=ECO:0000250	195..205
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810