DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Snx16 and SNX13

DIOPT Version :9

Sequence 1:	NP_611252.1	Gene:	Snx16 / 37015	FlyBaseID:	FBgn0034265	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	NP_001337791.1	Gene:	SNX13 / 23161	HGNCID:	21335	Length:	968	Species:	Homo sapiens

Alignment Length:	377	Identity:	81/377 - (21%)
Similarity:	151/377 - (40%)	Gaps:	75/377 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 SVCGLDKRSQFREQKLLGRKCHSSPDLRQIGKYQNN---SLLRSKSEGDVSLILASNSGAPLTVA 115
            :|.|....:|.:.:.||.|        ::.||:|.|   .|||:.:.|.....|:..:...:||
Human   405 TVEGYRVTAQQQLEVLLSR--------QRDGKHQTNQTKGLLRAAAVGIYEQYLSEKASPRVTV- 460

  Fly   116 NAKSEVCLQRISSHSYEQSPRTP-----INKSE---MLGGARSHRDLTQSSY------------- 159
               .:..:.:::.....:.| ||     |.:..   ||...|.:....|::.
Human   461 ---DDYLVAKLADTLNHEDP-TPEIFDDIQRKVYELMLRDERFYPSFRQNALYVRMLAELDMLKD 521

  Fly   160 ----GNQAGGHSVDLESRSRTPRRMSECSLGYSQSSSRHTGSNSMFASQMTLSSGSVVPPVDPNA 220
                |:..|    |.||.:.:|..    |:..|.....:..|:........:|. :|....||.|
Human   522 PSFRGSDDG----DGESFNGSPTG----SINLSLDDLSNVSSDDSVQLHAYISD-TVYADYDPYA 577

  Fly   221 VLRVPIIGYEVMEERARFTAYKLRV--ENPETNDYWLVMRRYTDFVRLNSKLKQAFPNLT--LML 281
            |..|      ..:....:..|.:.|  .|..:.:.|...|||:||...:.::.:.|.:|:  |.|
Human   578 VAGV------CNDHGKTYALYAITVHRRNLNSEEMWKTYRRYSDFHDFHMRITEQFESLSSILKL 636

  Fly   282 PRKKLFGDNFNAVFLDNRVQGLQIFVNSVMAKEELRKCKLVREF-FCLDEPPSYSESMEECRAIF 345
            |.||.| :|.:..||:.|.:.|..::..::|.|.::....:..: :...|..:||:.    :..|
Human   637 PGKKTF-NNMDRDFLEKRKKDLNAYLQLLLAPEMMKASPALAHYVYDFLENKAYSKG----KGDF 696

  Fly   346 EAQEET-IEHLKLQIRNKNDLILSLQQKLREEMNE--------KEQLREAMK 388
            ..:.:| :..|:..:||.::.:.||...|.|.|.:        .|:|.:.:|
Human   697 ARKMDTFVNPLRNSMRNVSNAVKSLPDSLAEGMTKMSDNMGKMSERLGQDIK 748

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx16	NP_611252.1	PX_SNX16	219..329	CDD:132809	27/114 (24%)
SNX13	NP_001337791.1	PXA	97..284	CDD:214611
		RGS_SNX13	377..511	CDD:188674	25/118 (21%)
		PX_SNX13	557..687	CDD:132783	32/137 (23%)
		Nexin_C	803..911	CDD:312222
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900