DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snx16 and Snx21

DIOPT Version :9

Sequence 1:	NP_611252.1	Gene:	Snx16 / 37015	FlyBaseID:	FBgn0034265	Length:	407	Species:	Drosophila melanogaster
Sequence 2:	XP_030102304.1	Gene:	Snx21 / 101113	MGIID:	1917729	Length:	372	Species:	Mus musculus

Alignment Length:	178	Identity:	50/178 - (28%)
Similarity:	76/178 - (42%)	Gaps:	20/178 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 GNQAGGHSVDLESRSRTPRRMSECSLGYSQSSSRHTGSNSMFASQMTL---SSGSVVPPVDPNAV 221
            |:.|.|...:   ||..|.......|...|.......|.:....|..|   :|.:||.  ||.:
Mouse    78 GDGASGEDAE---RSPPPDGQRSSQLLARQLQDFWKKSRNTLVPQRLLFEVTSANVVK--DPPS- 136

  Fly   222 LRVPIIGYEVMEERARFTAYKLRVENPETNDYW--LVMRRYTDFVRLNSKLKQAF--PNLTLMLP 282
               ..:.:.:.||...:|   |.|..|...|..  .:.|||:||.||:..|::.|  |...:..|
Mouse   137 ---KYVAWVISEEPQLYT---LAVMGPGPPDRQPAQISRRYSDFERLHRNLQRQFRGPMSAISFP 195

  Fly   283 RKKLFGDNFNAVFLDNRVQGLQIFVNSVMAKEELRKCKLVREFFCLDE 330
            ||:| ..||.|..:..|.:..:.|:..:.|..|||:...:::||.|.|
Mouse   196 RKRL-RRNFTAETIARRSRAFEQFLGHLQAVPELRQAPDLQDFFVLPE 242

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snx16	NP_611252.1	PX_SNX16	219..329	CDD:132809	32/113 (28%)
Snx21	XP_030102304.1	PX_domain	121..241	CDD:383026	38/129 (29%)
		TPR_12	243..312	CDD:315987	50/178 (28%)
		TPR repeat	243..267	CDD:276809	50/178 (28%)
		TPR repeat	280..311	CDD:276809
		TPR repeat	325..352	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810