DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dlish and sh3glb1a

DIOPT Version :9

Sequence 1:	NP_611251.2	Gene:	Dlish / 37014	FlyBaseID:	FBgn0034264	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_009295790.1	Gene:	sh3glb1a / 792229	ZFINID:	ZDB-GENE-050417-89	Length:	398	Species:	Danio rerio

Alignment Length:	241	Identity:	49/241 - (20%)
Similarity:	78/241 - (32%)	Gaps:	83/241 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 KKATNASIERDLPAVGVLGMGRITGSSSIETLVRVGIEKEHGLSPDSKMVVLHDFTPCVDDELEV 78
            ::.|.|  |:||.    :........:.|..|:..||...|.          |... |::|.:|.
Zfish   221 EEVTTA--EQDLK----MTQSEFDRQAEITRLLLEGISSTHA----------HHLR-CLNDFVEA 268

  Fly    79 KRGQLVNILYRENDWVYVIGQDSRQEGFIPFSYCAPCNTQLADLAVKKKLPREQCPEQPIEENIP 143
            :                             .:|.|.|...:.||  :|:|           .|.|
Zfish   269 Q-----------------------------MTYYAQCYQYMVDL--QKQL-----------GNFP 291

  Fly   144 LLGTDNKLDVLCDETLNPGSANSIENTLLVEPECTPFVKEPSG---------------RCIVLYT 193
            ...|.|.    ...|.:.|:..|:.    :.|..||.....|.               :..|||.
Zfish   292 SAFTSNN----NQSTASGGAGVSVP----ILPLSTPLPSTTSNTSSGFTEMQNFSGSRKARVLYD 348

  Fly   194 FIARDENDLSVERGEFVTVLNREDPDWFWIMRSDG-QEGFVPASFI 238
            :.|...|:||:...|.:.|.:....|..|:|...| |:|.||.:::
Zfish   349 YDAAGSNELSLLADEVIMVSSVPGMDSDWLMGERGSQKGKVPITYL 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dlish	NP_611251.2	SH3	61..111	CDD:212690	4/49 (8%)
		SH3	184..238	CDD:214620	18/69 (26%)
		SH3	293..346	CDD:212690
sh3glb1a	XP_009295790.1	BAR	21..287	CDD:299863	20/113 (18%)
sh3glb1a	XP_009295790.1	SH3_Endophilin_B1	338..398	CDD:212878	17/57 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583885
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930