DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dlish and sh3glb2a

DIOPT Version :9

Sequence 1:	NP_611251.2	Gene:	Dlish / 37014	FlyBaseID:	FBgn0034264	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_017212791.1	Gene:	sh3glb2a / 402885	ZFINID:	ZDB-GENE-061201-8	Length:	390	Species:	Danio rerio

Alignment Length:	259	Identity:	55/259 - (21%)
Similarity:	100/259 - (38%)	Gaps:	69/259 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CPVRMRRDKKKATNASIERDL--------PAVGVLGMGRITGSSSIETLVRVGIEKEHGLSPDSK 61
            |..|:::.|.....|:.|.:.        |...||       |:|...|....::|    |....
Zfish   172 CKARLKKAKAAEAKAACEGEAVPDFQETRPRNYVL-------SASASALWSEELDK----SEQEL 225

  Fly    62 MVVLHDFTPCVDDELEVKRGQLVNILYRENDWVYVIGQDSRQEGFIPFSYCAPCNTQLADLAVKK 126
            .|...:|    |.:.||.|..|..|.....:.:..:.:.:..:..    |...|:..:      :
Zfish   226 RVAQAEF----DRQAEVTRLLLEGISSTHVNHLRCLREFAEAQAM----YYNQCHKYM------Q 276

  Fly   127 KLPRE--------QCPEQPIEENIPLLGTDNKLDVLCDETLNP----GSANSIE-NTLLVEPECT 178
            :|.||        :||:              .|:|.|:.:.:|    .|.:.:: :||.:|.
Zfish   277 ELQRELGSSSGDIRCPD--------------SLEVNCEPSGSPSDLLNSPSPLDSDTLQIEE--- 324

  Fly   179 PFVKEPSG---RCIVLYTFIARDENDLSVERGEFVTVLNREDPDWFWIMRSDG-QEGFVPASFI 238
              |:.|:.   :..|||.:.|.|.::||:...|.:||......|..|::...| |:|.||.:::
Zfish   325 --VQPPASGTRKARVLYDYTAADSSELSLRADELITVYTMPGMDSDWLIGERGNQKGKVPVTYL 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dlish	NP_611251.2	SH3	61..111	CDD:212690	8/49 (16%)
		SH3	184..238	CDD:214620	18/57 (32%)
		SH3	293..346	CDD:212690
sh3glb2a	XP_017212791.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583879
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930