Protein Alignment Dlish and Sh3rf3

DIOPT Version :10

• Sequence 1: NP_611251.2
• Gene: Dlish / 37014
• FlyBaseID: FBgn0034264
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: XP_017457292.1
• Gene: Sh3rf3 / 294557
• RGDID: 1589772
• Length: 878
• Species: Rattus norvegicus
• Alignment Length: 252
• Identity: 53/252 - (21%)
• Similarity: 101/252 - (40%)
• Gaps: 48/252 - (19%)

  Fly     4 LCPVRMRRDKKKATNASIERDLPAVGVLGMGRITGSSSIETLVRVGIEKEHGLSPDSKMVVLHDF 68
            :|| |.......|.:|....::.|..:.|....|.:|.:.|...:..    |..||.|
  Rat   655 MCP-RPAIPFTSAASAITPPNVSAANLSGEVGGTPTSGLSTPSPINA----GYKPDDK------- 707

  Fly    69 TPCVDDELEVKRGQLVNILYRENDWVYVIGQDSRQEGFIPFSYCAPCNTQLA-DLAVKKKLPREQ 132
                .:|.:.|:..|:.:|         .|..::::...|.|.....:.|.| |.:::..:..|.
  Rat   708 ----KNEKKEKKSGLLKLL---------AGASTKKKARSPPSVSPTHDPQSAMDSSLQGAVGPEV 759

  Fly   133 CP--------EQPIEENI-------PLLGTDNKLDVLCDETLNPGSANSIENTLLVEPECTPFVK 182
            .|        ..|:|..:       ||......||:  :.:|:| |..:..:|..:.||..|..:
  Rat   760 SPLTIHGRAGSCPVESEMQGAIGLEPLHRKAGSLDL--NFSLSP-SRQATLSTASIRPEPKPLPR 821

  Fly   183 EPSGRCIVLYTFIARDENDLSVERGEFVTVLNREDPDWF-WIMRSDGQEGFVPASFI 238
            |   |..|:.::..:.|.::.::.|:.|.|..:.:..|| ..::.:|:.|..|.||:
  Rat   822 E---RYRVVVSYPPQSEAEIELKEGDIVFVHRKHEDGWFKGTLQRNGRTGLFPGSFV 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dlish	NP_611251.2	SH3	61..111	CDD:212690	7/49 (14%)
		SH3	184..238	CDD:214620	12/54 (22%)
		SH3	293..346	CDD:212690
Sh3rf3	XP_017457292.1	RING-HC_SH3RF3	48..93	CDD:438408
		SH3	191..244	CDD:473055
		SH3	254..308	CDD:473055
		SH3	462..518	CDD:473055
		DUF5585	<516..831	CDD:465521	42/206 (20%)
		SH3_SH3RF_C	823..877	CDD:212719	13/53 (25%)