DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dlish and Sh3rf3

DIOPT Version :9

Sequence 1:	NP_611251.2	Gene:	Dlish / 37014	FlyBaseID:	FBgn0034264	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_017457292.1	Gene:	Sh3rf3 / 294557	RGDID:	1589772	Length:	878	Species:	Rattus norvegicus

Alignment Length:	252	Identity:	53/252 - (21%)
Similarity:	101/252 - (40%)	Gaps:	48/252 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LCPVRMRRDKKKATNASIERDLPAVGVLGMGRITGSSSIETLVRVGIEKEHGLSPDSKMVVLHDF 68
            :|| |.......|.:|....::.|..:.|....|.:|.:.|...:..    |..||.|
  Rat   655 MCP-RPAIPFTSAASAITPPNVSAANLSGEVGGTPTSGLSTPSPINA----GYKPDDK------- 707

  Fly    69 TPCVDDELEVKRGQLVNILYRENDWVYVIGQDSRQEGFIPFSYCAPCNTQLA-DLAVKKKLPREQ 132
                .:|.:.|:..|:.:|         .|..::::...|.|.....:.|.| |.:::..:..|.
  Rat   708 ----KNEKKEKKSGLLKLL---------AGASTKKKARSPPSVSPTHDPQSAMDSSLQGAVGPEV 759

  Fly   133 CP--------EQPIEENI-------PLLGTDNKLDVLCDETLNPGSANSIENTLLVEPECTPFVK 182
            .|        ..|:|..:       ||......||:  :.:|:| |..:..:|..:.||..|..:
  Rat   760 SPLTIHGRAGSCPVESEMQGAIGLEPLHRKAGSLDL--NFSLSP-SRQATLSTASIRPEPKPLPR 821

  Fly   183 EPSGRCIVLYTFIARDENDLSVERGEFVTVLNREDPDWF-WIMRSDGQEGFVPASFI 238
            |   |..|:.::..:.|.::.::.|:.|.|..:.:..|| ..::.:|:.|..|.||:
  Rat   822 E---RYRVVVSYPPQSEAEIELKEGDIVFVHRKHEDGWFKGTLQRNGRTGLFPGSFV 875

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dlish	NP_611251.2	SH3	61..111	CDD:212690	7/49 (14%)
		SH3	184..238	CDD:214620	12/54 (22%)
		SH3	293..346	CDD:212690
Sh3rf3	XP_017457292.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343642
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930