DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dlish and Sh3glb1

DIOPT Version :9

Sequence 1:	NP_611251.2	Gene:	Dlish / 37014	FlyBaseID:	FBgn0034264	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_006233493.1	Gene:	Sh3glb1 / 292156	RGDID:	1304859	Length:	402	Species:	Rattus norvegicus

Alignment Length:	212	Identity:	47/212 - (22%)
Similarity:	78/212 - (36%)	Gaps:	54/212 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RITGS-----SSIETLVRVGIEKEHGLSPDSKMVVLHDFTPCVDDELEVKRGQLVNILYRENDWV 94
            |||.|     :.|..|:..||...|.          |... |::|.:|.:
  Rat   233 RITQSEFDRQAEITRLLLEGISSTHA----------HHLR-CLNDFVEAQ--------------- 271

  Fly    95 YVIGQDSRQEGFIPFSYCAPCNTQLADLAVKKKLPREQCPEQPIEENIPLLGTDNKLDVLCDETL 159
                          .:|.|.|...:.||  :|:|  ...|...:..|....||  .:......|:
  Rat   272 --------------MTYYAQCYQYMLDL--QKQL--GSFPSNYVSNNNQTSGT--PVPYTLSNTI 316

  Fly   160 NPGSANSIENTLLVEPECTPFVKEPSG--RCIVLYTFIARDENDLSVERGEFVTVLNREDPDWFW 222
            .|.:..|..:.::..|.....:|:.|.  :..|||.:.|.:..:||:...|.:||.:....|..|
  Rat   317 GPSAVASTGSLVITCPPNLSDLKDSSSTRKARVLYDYDAANSTELSLLADEVITVFSVVGMDSDW 381

  Fly   223 IMRSDG-QEGFVPASFI 238
            :|...| |:|.||.:::
  Rat   382 LMGERGNQKGKVPITYL 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dlish	NP_611251.2	SH3	61..111	CDD:212690	4/49 (8%)
		SH3	184..238	CDD:214620	18/56 (32%)
		SH3	293..346	CDD:212690
Sh3glb1	XP_006233493.1	BAR_Endophilin_B1	24..289	CDD:153300	19/97 (20%)
Sh3glb1	XP_006233493.1	SH3_Endophilin_B1	342..402	CDD:212878	18/57 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343634
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930