Protein Alignment Dlish and SORBS3

DIOPT Version :9

• Sequence 1: NP_611251.2
• Gene: Dlish / 37014
• FlyBaseID: FBgn0034264
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: XP_006716329.1
• Gene: SORBS3 / 10174
• HGNCID: 30907
• Length: 710
• Species: Homo sapiens
• Alignment Length: 337
• Identity: 71/337 - (21%)
• Similarity: 120/337 - (35%)
• Gaps: 110/337 - (32%)

  Fly    67 DFTPCVDDELEVKRGQLVNILYRENDWVYVIGQDSRQEGFIPFSYCAPCNTQLADLAVKKKLPRE 131
            ||......||.:::|.:|.| ::|.|..::.|:...:.|..|.:|.             :.||.:
Human   429 DFQAQSPKELTLQKGDIVYI-HKEVDKNWLEGEHHGRLGIFPANYV-------------EVLPAD 479

  Fly   132 QCPEQPIEENIPLLGTDNKLDVLCDETLNPGSANSIENTLLVEPECTPFVKEPSGRCIVLYTFIA 196
            :.| :||:                     |.:...:|                .|..:..|||..
Human   480 EIP-KPIK---------------------PPTYQVLE----------------YGEAVAQYTFKG 506

  Fly   197 RDENDLSVERGEFVTVLNREDPDWF-WIMRSDGQEGFVPASFIY--------------------- 239
            ..|.:||..:||.:.::.:.:.:|: ..:...|::|..|||::.
Human   507 DLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQVSREPRLRLCDDGPQLPTSPR 571

  Fly   240 ---PADSVRVLQQQKATLNAMETILQQGQQGQQ------SQQQQQPQ------------------ 277
               .|.|.|......|..:..:.|...||...:      ..|:.:||
Human   572 LTAAARSARHPSSPSALRSPADPIDLGGQTSPRRTGFSFPTQEPRPQTQNLGTPGPALSHSRGPS 636

  Fly   278 --LGLGT---DDLRYHGTELVMLYDYKAQAPDDLYLSVRRGDWIYADLTNQTVDGWLWAYAPKTR 337
              |.|||   :..:.|.|....:|.|:.|..|:|.|  |.||.:  |:..|..|||....:.:|:
Human   637 HPLDLGTSSPNTSQIHWTPYRAMYQYRPQNEDELEL--REGDRV--DVMQQCDDGWFVGVSRRTQ 697

  Fly   338 KYGFIPKAYARP 349
            |:|..|..|..|
Human   698 KFGTFPGNYVAP 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dlish	NP_611251.2	SH3	61..111	CDD:212690	12/43 (28%)
		SH3	184..238	CDD:214620	15/54 (28%)
		SH3	293..346	CDD:212690	18/52 (35%)
SORBS3	XP_006716329.1	Sorb	155..204	CDD:128735
		AC_N	337..>412	CDD:292831
		SH3_Vinexin_1	422..476	CDD:212854	13/60 (22%)
		SH3_Vinexin_2	496..551	CDD:212857	15/54 (28%)
		SH3_Vinexin_3	653..710	CDD:212851	21/61 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149751
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840