Protein Alignment Dlish and sh3rf2

DIOPT Version :10

• Sequence 1: NP_611251.2
• Gene: Dlish / 37014
• FlyBaseID: FBgn0034264
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: XP_031754675.1
• Gene: sh3rf2 / 100497897
• XenbaseID: XB-GENE-5763588
• Length: 732
• Species: Xenopus tropicalis
• Alignment Length: 311
• Identity: 60/311 - (19%)
• Similarity: 108/311 - (34%)
• Gaps: 116/311 - (37%)

  Fly   141 NIPLLGTDNKLDVL-----CDETLNPGSANSIENTLLVEPECT-PFVKEPSGRCIVLYTFIARDE 199
            |.|...|.||.|::     .||..|.|.||....   :.||.: .|:::....|..:|.|..:::
 Frog   139 NSPRDLTLNKGDIIVLHRQLDENWNNGQANRGSR---IFPETSGKFLQQAPALCKAMYNFDVKEK 200

  Fly   200 ND-----LSVERGEFVTVLNREDPDWFWIMRSDG----QEGFVPASFIYPADS------------ 243
            |.     |..::.:.::|:.|.|.:|     ::|    |.|..|..|:.|..:
 Frog   201 NRESKDCLKFQKDDVISVIRRVDENW-----AEGKLGDQVGIFPLMFVEPNQTAKQLLESKKNRS 260

  Fly   244 ---------VRVLQQQKATLNAMETILQQGQQ-----------------------GQQSQQQQQP 276
                     ::|..:.|.|..|....:|:|::                       |:|:.:...|
 Frog   261 NHNNALYPLIKVPSKVKGTEVAPNHTMQEGRRKGPRQFLITNALNRFNKMVHSPTGRQTPEISSP 325

  Fly   277 QL--------------------GLGTDDLRYH---GTE--------------------LVMLYDY 298
            .|                    .|.|.:  |:   ||:                    .|:|:.|
 Frog   326 ILISSSNPAVIEKAEALSSSPAQLNTSN--YYPTFGTQSNGTPFMALPSSHQTILANMCVVLHPY 388

  Fly   299 KAQAPDDLYLSVRRGDWIYADLTNQTVDGWLWAYAPKTRKYGFIPKAYARP 349
            .|..|::  :.::||:.:  .:..:..:|||...:..|.|.|..|.....|
 Frog   389 MANGPEE--MDLQRGEGV--RILGKFQEGWLRGVSLVTGKIGLFPSHCVSP 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dlish	NP_611251.2	SH3	61..111	CDD:212690
		SH3	184..238	CDD:214620	13/62 (21%)
		SH3	293..346	CDD:212690	14/52 (27%)
sh3rf2	XP_031754675.1	RING_Ubox	17..55	CDD:473075
		SH3	131..178	CDD:473055	14/41 (34%)
		SH3	188..243	CDD:473055	13/59 (22%)
		SH3_SH3RF2_3	381..435	CDD:212718	14/57 (25%)