Protein Alignment CG6424 and fam13b

DIOPT Version :10

• Sequence 1: NP_611249.2
• Gene: CG6424 / 37012
• FlyBaseID: FBgn0028494
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: NP_001314971.1
• Gene: fam13b / 568603
• ZFINID: ZDB-GENE-030131-4913
• Length: 961
• Species: Danio rerio
• Alignment Length: 874
• Identity: 203/874 - (23%)
• Similarity: 314/874 - (35%)
• Gaps: 270/874 - (30%)

  Fly   100 SAFGQDRKLQRSNSEELLTEPAAIVSSTAQAAAELLEAQCEVIRRVSSEDFKRTASYANYRQEF- 163
            :.||.|.....::.|:|..:     .|.::..|||||.|.|.... ..||...|..|::...:.
Zfish   172 AVFGPDIFHLDTDVEDLKEQ-----ESVSRILAELLENQEEFFES-EDEDISNTNDYSSINDQIT 230

  Fly   164 ----EREQEECSEL---GENN-------------------ASLANLP--------TGEAAKERPR 194
                |.:.:.|.||   ||:.                   ||::.||        |..||.|:..
Zfish   231 ELLEEEKLDACEELPRDGEDGPSSLSPKHAQVAPSSSSHIASISILPGSADIIQRTIRAAVEQHL 295

  Fly   195 LE------------------------TSPARQAP-----KEASDDSECEHERRRSSERFCKSRQP 230
            |:                        .||..:.|     ::...:||.|.|           ..|
Zfish   296 LDLQTSIDKELGSYESQVLDSKPIHGNSPTLKTPGPEDHEDVQSESEAETE-----------TLP 349

  Fly   231 PVRKSGVAKKVGGGS-GSKYLPSRRDEQSAYKYD---------LSALKYERRGFISSRKQQQNQT 285
            .|.:.|:..:....| ||:......:|.|....|         |.|.:.|:.    |..:|.:||
Zfish   350 EVTEEGLPSENSEESQGSQLSSPIMEESSGMDLDTETLIETESLGAERLEKH----SDYEQMDQT 410

  Fly   286 QAMQSAADHNDNNLIDFHQQQKELQSKRSASISPTPTTSSSAGS-------DDSTPTS------- 336
            .......|..|.|             ..|.|..|.....||..|       :.|.|.:
Zfish   411 DVTTCEPDDCDLN-------------ANSESTEPASGFQSSTRSMFLEGEQEASCPINFPPIDFT 462

  Fly   337 --------NAPAPIKAKPQRQQQSLD-----LTSAQESLPWERGDEPAPILSRR---YAHSRPHI 385
                    |.|.|:....|.:.:|.:     |......||.|  ::..|:|:||   :.||:..:
Zfish   463 CMHLQREGNDPMPVFMSWQEETESGEAQLSPLAGRMMPLPLE--EDAHPLLARRFLDFGHSQRFL 525

  Fly   386 GGNLDAAAKLAKVMPYPQQLPKQASTVQLHSDITDMDCCLEPMDAVRAFSSLENMRTRDVMQQVL 450
            ..:.||:                :||..|        .|..|..|  :.||.::::..:|.||
Zfish   526 QQDHDAS----------------SSTKTL--------SCGRPRRA--SLSSKDSVKGDNVSQQ-- 562

  Fly   451 PAMMGAFQTPEDRVKAINRRVTVLKKKLVQLEESLEQRLGYRPSQAERLNDKYMKNALAELSKLR 515
                            :.:::..||||:.|.:|..|:...|:||.|::..|..:...:.:|:|:|
Zfish   563 ----------------LTKKLQNLKKKIKQFDEQFEKERNYKPSHADKAADPKVLKWMTDLTKIR 611

  Fly   516 KE---RHEL------------------------KTDPIAALGLKVGS------------------ 535
            |:   ||.|                        ...|...|...:.|
Zfish   612 KQLKGRHHLLPKGSLRHQAVLQSYRCHSSSSSVPNTPHITLSRPLASRQSPHFYAKHKAESELTP 676

  Fly   536 -------------GGGAGIGGQEVAKKLE------RMKATLAEIEQNLNEKRVNGHRSEQLEDLN 581
                         |........|...::|      ..:.||..|:|.:..||......|.:..:.
Zfish   677 QTRPRSNTLPKSFGSTLDQSAYEDTVEIEARGHRPTREETLELIQQCIQSKRDEDGWPEDVRKMT 741

  Fly   582 ADQLVQEKSAVQHGLLYFESLYGHPITKEERDAARPLYDRYRQLKRLVSRTVMFGAGTGIPELPT 646
            .:||..||:.:|..|||:|.|:|.|:|:|||...:|||||||.:|::::|..:    |.|...|:
Zfish   742 KEQLASEKTVLQKNLLYYEGLHGRPVTREERLIVKPLYDRYRLVKQMLTRVSI----TPIIASPS 802

  Fly   647 ILEHEAMVFEATSTPLQYSSNNSTETTNSPSDSNAPNTLTQNASSDESTTTTTLTGPATGNSA-- 709
            ......|:.........:......|...........|...|:..||      .:..|....|:
Zfish   803 SKRRNQMLQPIIEGETAHFCGEIEEEEEDEGRGQQENVEMQSECSD------IIMDPVAQPSSQH 861

  Fly   710 TSQENQAAS---------ENIAALSVDQLWEQLDRARDEKSLLKSTIREYESLFEEQNGRKMLKQ 765
            .:|||..:|         .:..|.|:.:|.|||.:||.||..|:.||||:|..|.:||||.:.|:
Zfish   862 PTQENILSSGKLNLDLRLSSTNASSMPELLEQLWKARAEKKKLRRTIREFEDEFYQQNGRNVQKE 926

  Fly   766 DRRSLETETYAQYKEKKAKVRLLQALIKK 794
            ||..:..| |.:||..|||:|||:.||.|
Zfish   927 DRLPMMDE-YKEYKRIKAKLRLLEVLISK 954

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6424	NP_611249.2	PRK02224	<462..626	CDD:179385	55/227 (24%)
fam13b	NP_001314971.1	RhoGAP_FAM13A1a	17..204	CDD:239858	10/36 (28%)
		RecQL4_SLD2_NTD	566..615	CDD:412085	16/48 (33%)