DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment swi2 and Lapsyn

DIOPT Version :9

Sequence 1:	NP_611247.3	Gene:	swi2 / 37010	FlyBaseID:	FBgn0034262	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_611561.1	Gene:	Lapsyn / 37418	FlyBaseID:	FBgn0034602	Length:	343	Species:	Drosophila melanogaster

Alignment Length:	217	Identity:	49/217 - (22%)
Similarity:	82/217 - (37%)	Gaps:	62/217 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 QMLMVMHYKLELKRQCQSHEDLRNCTCLMHHILPKTHIPLYTVNCSHLQFHRLPDFLPDNTTTLV 312
            ::|.:..|.|:||...|:.:.......|.|:.:.|    |.|.:     |.|..|.     ..|:
  Fly    38 KLLRIRCYDLDLKEVPQNLKSSVEVLDLSHNRIRK----LKTSS-----FQRYTDI-----KFLM 88

  Fly   313 INDNMISDI-----NPLRDNPHYRHVVDMQLENNQISNVDNLEDTYWLQNFRLLNLRGNNLRKLH 372
            :.||||..:     .||..      :.::.|.||.::.:. || .:.|...|.|.:..|.|..|:
  Fly    89 LYDNMILSVEVGTFEPLTS------LQEIDLSNNGLTTIP-LE-LFQLPRLRNLYIDSNELTSLN 145

  Fly   373 VYALDNALDDNENANLLLLSRNPWHCTCKFGSRMRELLTKYKD--IVRDAWNVSCT------YRL 429
            :.||:..:            |.|.......|..::||    .|  |:...|.::.:      :|:
  Fly   146 LQALEKPI------------RAPLEYLNVAGCELQEL----PDLGILPKLWQLNASMNPLQNFRI 194

  Fly   430 DDDQLLAKVLTLSRQEMCNLSV 451
            |           |...||:|.|
  Fly   195 D-----------SLANMCHLQV 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
swi2	NP_611247.3	LRR	<117..384	CDD:227223	34/140 (24%)
		leucine-rich repeat	132..154	CDD:275378
		leucine-rich repeat	155..178	CDD:275378
		leucine-rich repeat	179..201	CDD:275378
		leucine-rich repeat	202..214	CDD:275378
		leucine-rich repeat	287..307	CDD:275378	5/19 (26%)
		leucine-rich repeat	308..332	CDD:275378	7/28 (25%)
		leucine-rich repeat	333..357	CDD:275378	6/23 (26%)
		leucine-rich repeat	358..385	CDD:275378	7/26 (27%)
		leucine-rich repeat	386..398	CDD:275378	2/11 (18%)
Lapsyn	NP_611561.1	leucine-rich repeat	39..59	CDD:275380	6/19 (32%)
		LRR_8	58..118	CDD:290566	18/79 (23%)
		leucine-rich repeat	60..83	CDD:275380	7/31 (23%)
		leucine-rich repeat	84..107	CDD:275380	7/27 (26%)
		LRR_RI	<94..>249	CDD:238064	31/147 (21%)
		LRR_8	106..167	CDD:290566	16/80 (20%)
		LRR_4	106..145	CDD:289563	10/46 (22%)
		leucine-rich repeat	108..130	CDD:275380	6/23 (26%)
		leucine-rich repeat	131..154	CDD:275380	7/34 (21%)
		leucine-rich repeat	157..178	CDD:275380	5/24 (21%)
		leucine-rich repeat	179..202	CDD:275380	5/33 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24366
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100