DRSC/TRiP Functional Genomics Resources

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Protein Alignment swi2 and LRRC66

DIOPT Version :9

Sequence 1:NP_611247.3 Gene:swi2 / 37010 FlyBaseID:FBgn0034262 Length:499 Species:Drosophila melanogaster
Sequence 2:NP_001019782.1 Gene:LRRC66 / 339977 HGNCID:34299 Length:880 Species:Homo sapiens


Alignment Length:178 Identity:44/178 - (24%)
Similarity:71/178 - (39%) Gaps:40/178 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 TLKCYGGMNNLAALNQSGKLSRVQPALEML--LCGWPKDGLNHFRD------------------- 125
            ||..:..::.|..||.|..... ..:|::|  ...|.|...:.||:                   
Human   101 TLSPFAYLHALEVLNLSNNAIH-SLSLDLLSPKSSWVKRHRSSFRNRFPLLKVLILQRNKLSDTP 164

  Fly   126 --LQKLPRLRSLTIEYSGFTEFKF-DFPEMLELHTINISWTNLSYISSRTFKRVHPLKVLDLRWN 187
              |.||..|:||.:.::|..:..: ||...|:|..:.:....:..|..:.||.:..|:|:||..|
Human   165 KGLWKLKSLQSLDLSFNGILQIGWSDFHNCLQLENLCLKSNKIFKIPPQAFKDLKKLQVIDLSNN 229

  Fly   188 QLIQLDGPLLLPRNFEQLY--LAGNPWNCT------RNF-------KW 220
            .||.:...:::...|..|.  ||.|.|.|.      :||       ||
Human   230 ALITILPMMIIALEFPHLVVDLADNNWQCDDSVAVFQNFISESWRKKW 277

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
swi2NP_611247.3 LRR <117..384 CDD:227223 35/141 (25%)
leucine-rich repeat 132..154 CDD:275378 6/22 (27%)
leucine-rich repeat 155..178 CDD:275378 4/22 (18%)
leucine-rich repeat 179..201 CDD:275378 7/21 (33%)
leucine-rich repeat 202..214 CDD:275378 6/13 (46%)
leucine-rich repeat 287..307 CDD:275378
leucine-rich repeat 308..332 CDD:275378
leucine-rich repeat 333..357 CDD:275378
leucine-rich repeat 358..385 CDD:275378
leucine-rich repeat 386..398 CDD:275378
LRRC66NP_001019782.1 LRR_RI 60..>255 CDD:238064 37/154 (24%)
leucine-rich repeat 64..86 CDD:275380
LRR_8 86..160 CDD:290566 12/59 (20%)
LRR 1 86..107 2/5 (40%)
leucine-rich repeat 88..110 CDD:275380 2/8 (25%)
LRR 2 110..130 5/20 (25%)
leucine-rich repeat 111..149 CDD:275380 10/38 (26%)
LRR 3 149..171 2/21 (10%)
leucine-rich repeat 150..172 CDD:275380 3/21 (14%)
LRR_8 171..231 CDD:290566 16/59 (27%)
LRR 4 172..193 6/20 (30%)
leucine-rich repeat 173..196 CDD:275380 6/22 (27%)
LRR 5 196..217 3/20 (15%)
leucine-rich repeat 197..220 CDD:275380 4/22 (18%)
LRR 6 220..241 7/20 (35%)
leucine-rich repeat 221..242 CDD:275380 7/20 (35%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 319..368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 463..504
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 679..746
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 764..816
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 855..880
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24366
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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