DRSC/TRiP Functional Genomics Resources

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Protein Alignment swi2 and igsf10

DIOPT Version :9

Sequence 1:NP_611247.3 Gene:swi2 / 37010 FlyBaseID:FBgn0034262 Length:499 Species:Drosophila melanogaster
Sequence 2:XP_009289666.1 Gene:igsf10 / 100329456 ZFINID:ZDB-GENE-130530-827 Length:2497 Species:Danio rerio


Alignment Length:292 Identity:64/292 - (21%)
Similarity:108/292 - (36%) Gaps:106/292 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   274 CLMHHI--LPKTHIPLYTVNCSHLQFHRLPDFLPDNTTTLV------------INDNMISDINPL 324
            ||.|..  .||:.: .|..:..|..|..|.: :|.:..|.|            :..|.:|.:|.|
Zfish    23 CLTHRSSGCPKSCV-CYAPSEVHCTFRYLSE-MPGDIQTAVERINLGYNSLSSLQANALSGLNKL 85

  Fly   325 R------------------------------------DNPHYR---HVVDMQLENNQISNVDNLE 350
            .                                    :...:|   ::|.:||::|.|:.: :.|
Zfish    86 ELLMLHSNMIKTVEDSAFSGLTSLQVLKMSYNRVEKLNKDTFRGLDNLVRLQLDHNLITFI-HPE 149

  Fly   351 DTYWLQNFRLLNLRGNNLRKLH--------------------VYALDNALDDNENANL------- 388
            ..|.|:..:|:||.||.|::||                    :|..||||.....|.|       
Zfish   150 SFYGLKRLQLINLEGNQLQQLHPDTFISVRFGQILKWSSLKTIYLSDNALGTLPAAVLSGCVKIE 214

  Fly   389 -LLLSRNPWHCTCKFGSRMRELLTKYKDIV---RDAWNVS-----CTYRLDDD-----QLLAKVL 439
             |.||.|||.|.|:. |.:.:.:.|:..::   ||...:.     |.:.|...     ||.:...
Zfish   215 NLFLSGNPWSCDCRM-SWLAKWIEKHPGVLKCKRDKKFLKEPCPICEFPLSSRGSSIVQLQSDGY 278

  Fly   440 TLSRQE------MCNLSVEGG--TQIHPIDWL 463
            |.||.:      :.|.::..|  |::.|:|::
Zfish   279 TCSRPQIKPYLKLRNFTMTDGDYTEVSPVDFV 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
swi2NP_611247.3 LRR <117..384 CDD:227223 38/182 (21%)
leucine-rich repeat 132..154 CDD:275378
leucine-rich repeat 155..178 CDD:275378
leucine-rich repeat 179..201 CDD:275378
leucine-rich repeat 202..214 CDD:275378
leucine-rich repeat 287..307 CDD:275378 5/19 (26%)
leucine-rich repeat 308..332 CDD:275378 7/74 (9%)
leucine-rich repeat 333..357 CDD:275378 8/23 (35%)
leucine-rich repeat 358..385 CDD:275378 13/46 (28%)
leucine-rich repeat 386..398 CDD:275378 8/19 (42%)
igsf10XP_009289666.1 LRR_8 61..119 CDD:290566 5/57 (9%)
leucine-rich repeat 61..84 CDD:275380 3/22 (14%)
leucine-rich repeat 85..108 CDD:275380 1/22 (5%)
LRR_8 107..167 CDD:290566 14/60 (23%)
leucine-rich repeat 109..132 CDD:275380 1/22 (5%)
leucine-rich repeat 133..156 CDD:275380 8/23 (35%)
leucine-rich repeat 157..188 CDD:275380 8/30 (27%)
leucine-rich repeat 189..212 CDD:275380 7/22 (32%)
TPKR_C2 221..>238 CDD:301599 6/17 (35%)
Ig 490..557 CDD:299845
IG_like 492..571 CDD:214653
IG_like 590..652 CDD:214653
Ig 594..655 CDD:143165
IG_like 1529..1612 CDD:214653
Ig 1538..1611 CDD:299845
I-set 1621..1709 CDD:254352
Ig 1632..1709 CDD:299845
IG_like 1724..1806 CDD:214653
Ig 1729..1806 CDD:299845
I-set 1813..1898 CDD:254352
Ig 1833..1905 CDD:299845
I-set 1918..2009 CDD:254352
Ig 1928..2009 CDD:299845
IG 2022..2101 CDD:214652
IGc2 2028..2093 CDD:197706
I-set 2118..2203 CDD:254352
Ig 2134..2203 CDD:299845
IG_like 2218..2303 CDD:214653
IGc2 2225..2293 CDD:197706
I-set 2307..2397 CDD:254352
Ig <2337..2397 CDD:299845
IG_like 2409..2496 CDD:214653
Ig 2420..2493 CDD:143165
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24366
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.100

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