Protein Alignment Sema1b and sema3b

DIOPT Version :9

• Sequence 1: NP_001163178.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_001121818.1
• Gene: sema3b / 567064
• ZFINID: ZDB-GENE-081105-78
• Length: 775
• Species: Danio rerio
• Alignment Length: 579
• Identity: 183/579 - (31%)
• Similarity: 279/579 - (48%)
• Gaps: 66/579 - (11%)

  Fly    63 ILDHNDEFVLVGAKDVIYNVSLNGL-KEIARLEWHSTDADRELCALKGKH-EWDCHNYLRVYALR 125
            :||.....:.|||::.:.::||:.: |:..::.|.:....||.|...||. ..||.||::|....
Zfish    59 LLDEERGRLFVGARNFLLSLSLDNISKQEQKIYWPAPVDWREECNWAGKDINTDCVNYVKVLHHY 123

  Fly   126 PNGEVLLCGTNSYKPRCRHYTPVEVSSEEAGSAGHAHAMRYEVSRDVEAQGLCPYSPAHNSTYAF 190
            ....:..|||.::.|.|.:.        |.|.....|..|.:.|...:.:|..||.|.|.|....
Zfish   124 NRTHLYACGTGAFHPTCAYV--------EVGQKMEDHVFRIDPSLVEDGKGKSPYDPRHTSASVL 180

  Fly   191 ADGHLYSATVADFSGGDPLIYRE-----NLRTEQYDLKQLNQPDFVGAI-------ERNGYVLFF 243
            ....||:....|..|.|..|:|.     ::||||:|.:.||:|.|:.|.       ..:..|.||
Zfish   181 IGDELYAGVATDLMGRDFTIFRSMGQKPSIRTEQHDSRWLNEPKFIAAFGVPESDNPDDDKVFFF 245

  Fly   244 FRELSMEVMNFGKAVYSRVARVCKNDRGGPYSHGKSWTSFLKARLNCSVPGE--FPFYFDEIQAI 306
            |||.::|...|||..|||:.::|:||.||..|....||:||||||.|||||.  ...:|||::.:
Zfish   246 FRETAVEAQGFGKVTYSRIGQLCRNDMGGQRSLVNKWTTFLKARLVCSVPGNDGTETHFDELRDV 310

  Fly   307 SPIVESGSKS-LIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWLPVEREQVPK 370
            ..:.....|: |||.|||||.:...|||||.:.::||..||.|.|..::.....|:|.: .:||.
Zfish   311 FLLQTRDKKNPLIYTVFTTSSSVFQGSAVCLYTMNDIRRAFLGPFAHKEGPNYQWIPFQ-GKVPY 374

  Fly   371 PRPGQC-------VEDSRTLTSIAVNFIKNHPLMEEAVPAVHGRPLLTKVNLHHRLTAIAVHPQV 428
            ||||.|       .|.::......:.|.::||||...|..:.||||..:..:.:..|.|.| .:|
Zfish   375 PRPGMCPSKTFGSFESTKGFPDNVIQFARHHPLMFNPVTPLGGRPLFLRTGIPYTFTQITV-DRV 438

  Fly   429 KSLSGAYYDVIYSGTDDGKVTKFINILSTHPNSTVDRLKTVVISEMQVLPLGTPIRELVISTSKN 493
            .:..| :|||::.|||.|.|.|.|::.....::|     .:::.|:.|....:.|..:.||:.:.
Zfish   439 NAADG-HYDVMFIGTDVGSVLKVISVPKGSWSNT-----ELLLEELHVFKDSSSIISMQISSKRQ 497

  Fly   494 SLVVVSDGSLVSVPLHHCS-HIVDCLGCLSLQDPICAWDLQTHEC-KNLATSQHKF-------GT 549
            .|.|.||..:|.||||.|| :...|..|...:||.||||  .|.| :.|..::.:|       |.
Zfish   498 QLYVGSDTGVVQVPLHRCSMYGKACAECCLARDPYCAWD--GHTCTRYLPNTKRRFRRQDVRNGD 560

  Fly   550 KTYLQSLNSTKK-------------AAALLCPHIPRDAPGAETVSFVTMAPPPTEEQKL 595
            ...|.|.:..|:             ::.|.|  :|:......|.::..:...|.||.:|
Zfish   561 PNALCSGDHQKQRVLEKRLYAVDGSSSFLEC--VPKSLQAQITWTYQKLPENPREEVRL 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_001163178.1	Sema_1A	55..511	CDD:200498	157/471 (33%)
		PSI	510..>537	CDD:214655	11/27 (41%)
sema3b	NP_001121818.1	Sema	46..515	CDD:301699	157/471 (33%)
		PSI	514..>550	CDD:214655	13/37 (35%)
		Ig_Semaphorin_classIII	574..664	CDD:143279	8/46 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910