Protein Alignment Sema1b and si:ch211-129c21.1

DIOPT Version :10

• Sequence 1: NP_611244.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_001428420.1
• Gene: si:ch211-129c21.1 / 563087
• ZFINID: ZDB-GENE-030131-5796
• Length: 791
• Species: Danio rerio
• Alignment Length: 779
• Identity: 201/779 - (25%)
• Similarity: 344/779 - (44%)
• Gaps: 142/779 - (18%)

  Fly    26 SGLTIVAGWMPDVKPDLQTKQDKVLAHFIGNSTDYFKILDHNDEFVLV-GAKDVIYNVSLNGLK- 88
            |.|.|:|      :..:|.:.:..:........:|..:|...|..:|| ||::.::.:.:|.:.
Zfish    22 SSLDIIA------RKTIQYEDNHAITFKEQGIWNYSTMLIREDLGLLVLGAREAVFALDINDISV 80

  Fly    89 EIARLEWHSTDADRELCALKGKH-EWDCHNYLRVYALRPNGEVLLCGTNSYKPRCRHYTPVEVSS 152
            ..:::.|..|:..::.|..|||| :.|||||:|:.....:..:.:||||::.|.|.:.|
Zfish    81 SRSKVLWKVTEEKQKECTSKGKHPDIDCHNYIRMLHQMNDSVMYICGTNAFSPTCDYIT------ 139

  Fly   153 EEAGSAGHAHAMRYEVSRDVEAQGLCPYSPAHNSTYAFADGHLYSATVADFSGGDPLIYRENLRT 217
                   :.:.......:..:.:|.||:.|...|:....|..|||||..:|.|.:|:|.|.:..|
Zfish   140 -------YDNGQLQLEGKQEDGRGKCPFDPFQRSSSVMVDQDLYSATSLNFLGSEPVILRTSPIT 197

  Fly   218 EQYDLKQ--LNQPDFV--GAIER--------NGYVLFFFRELSMEVMNFGKAVYSRVARVCKNDR 270
            .:..||.  ||:|:|:  .|:..        :..:..||.|.::|...:.|.|.||||||||.|.
Zfish   198 LRTLLKSSWLNEPNFIYMDAVPESEDSPEGDDDKIYMFFSENAIEYDFYNKLVVSRVARVCKGDM 262

  Fly   271 GGPYSHGKSWTSFLKARLNCSVP-GEFPFYFDEIQAISPIVESGSKSLIYAVFTT-SVNAIPGSA 333
            ||..:..:.|||||||||:|||| ...|:...::..:..  :...||:.||:||: |.:....||
Zfish   263 GGLRTLQRKWTSFLKARLDCSVPEPSLPYVIQDVFHVRH--QKWRKSVFYAIFTSQSSSTDQSSA 325

  Fly   334 VCAFNVDDILAAFD-GEFKSQ---KDSQSHWLPVEREQVPKPRPGQCVEDSRTLTSI-------- 386
            |||:||.||...|. |:||::   :.|...|:....: :|.||||.|:.::...:.|
Zfish   326 VCAYNVTDISNVFSRGKFKTEVAVEMSDVKWVTYSGD-LPVPRPGDCINNAARTSGIKSSMNIPD 389

  Fly   387 -AVNFIKNHPLMEEAVPAVHGRPLLTKVNLHHRLTAIAVHPQVKSLSGAYYDVIYSGTDDGKVTK 450
             .:.||::.|||::||..:.|:|||.|..  ..||.:.| ..|.:..|..|.:::.||.:|.|.|
Zfish   390 KTLQFIRDRPLMDDAVHPITGKPLLLKRG--PLLTRLVV-DMVTAADGQSYPMMFVGTANGYVQK 451

  Fly   451 FINILSTHPNSTVDRLKTVVISEMQVLPLGTPIRELVISTSKNSLVVVSDGSLVSVPLHHCSHIV 515
            .:|...          :..:|.|:::......|.  |:...:|.|...|...:|.:|:.:||...
Zfish   452 AVNYDG----------EMHIIEEVKLFESEEAID--VLRLHQNQLYAGSASGVVQMPVSNCSRYS 504

  Fly   516 DCLGCLSLQDPICAWDLQTHECKNL-ATSQHKFGTKTYLQSLNSTKKAAALLCPHIPRDAPGAET 579
            .||.|:..:||.||||:....|... |:::|   .|:.|  :.|.|...|..||......|...|
Zfish   505 SCLDCVLARDPYCAWDVPAQRCSRFPASTEH---AKSNL--IQSLKDGDATQCPITAPIEPKVRT 564

  Fly   580 VSF--------------------VTMAPPPTEEQK-------LLYSNVGSSQ-GNQPSLEQQPTG 616
            :..                    :...|.|...:|       :|.||..|:. |....:..:...
Zfish   565 LVLGNNIRLLCRPDSNLAQVNWNLAGKPLPYSNRKYTIYNDAILISNASSADAGRYTCVSVEQAK 629

  Fly   617 GDDFG----------------LNKITLTSMDPDDIM------------PNLNDPQKSTASVDEIK 653
            |..:.                .:||..|...|::|.            |:::..|.|.:....::
Zfish   630 GKHYTKTLAIYDLREEVAVVVTDKIKTTLGIPNEIYTTSSGLIKPEEPPSVSKNQASESKWIAMQ 694

  Fly   654 YASTPSFMLLTTIVFFTFLVGGIAG-ICCVKAKSRLMEAQMDESHRNHFGKPMQFKHQNTGKDI 716
            .|.....:::..::.:...:|.|:. :||.:        |..:||    |...:.::::.|.|:
Zfish   695 VALAMLSIMMACLLIWNLYMGHISPFMCCGR--------QPIKSH----GNLPRMEYKSAGNDV 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_611244.1	Sema_1A	55..511	CDD:200498	145/485 (30%)
		PSI	510..>537	CDD:214655	11/26 (42%)
si:ch211-129c21.1	NP_001428420.1	None