Protein Alignment Sema1b and sema6ba

DIOPT Version :9

• Sequence 1: NP_001163178.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_001353244.1
• Gene: sema6ba / 562398
• ZFINID: ZDB-GENE-131024-1
• Length: 872
• Species: Danio rerio
• Alignment Length: 691
• Identity: 211/691 - (30%)
• Similarity: 316/691 - (45%)
• Gaps: 160/691 - (23%)

  Fly    73 VGAKDVIYNVSLNGLK--EI---ARLEWHSTDADRELCALKGKHEWDCHNYLRVYALRPNGEVLL 132
            :||:|.:|.|.|:.:.  |:   .:..|.|...|..:|.:|||||.:|.||::| .|..:|.:.:
Zfish    71 IGARDDLYRVELDHVSGDEMFYSKKRTWESNKNDIRICRMKGKHEEECRNYIKV-LLSHDGGLFV 134

  Fly   133 CGTNSYKPRCRHYT--PVEVSSEEAGSAGHAHAMRYEVSRDVEAQGLCPYSPAHNSTYAFADGHL 195
            ||||::.|.|.:||  .:|:                 |...:.....|||.|.|.:...||:|.|
Zfish   135 CGTNAFNPLCANYTRDTLEL-----------------VGEPISGMARCPYDPKHANVALFAEGSL 182

  Fly   196 YSATVADFSGGDPLIYRE-----NLRTEQYDLKQLNQPDFVGAIERNGYVLFFFRELSMEVMNFG 255
            ::.||.||...|.:|||.     .|||.::|.|...:|.||.|:|...::.|||||::||.....
Zfish   183 FTGTVTDFLAIDAVIYRSLGESPALRTIKHDSKWFREPYFVSAVEWGPHIYFFFREMAMEFNYLE 247

  Fly   256 KAVYSRVARVCKNDRGGPYS-HGKSWTSFLKARLNCSVPGEFPFYFDEIQAISPIVESGSKSLIY 319
            |.:.||||||||.|.||... ..:.||||||||||||:||:..|||:.:|:.|||:....:.:|.
Zfish   248 KVMVSRVARVCKGDLGGSQRVLERQWTSFLKARLNCSIPGDSHFYFNLLQSTSPIIRMQGRDVIL 312

  Fly   320 AVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWLPVEREQVPKPRPGQC-VEDSR-- 381
            .||:|..|:|||||||||::..:...|:|.||.||..:|.|.||..|.||:||||.| |:.||
Zfish   313 GVFSTPSNSIPGSAVCAFDMQQLARVFEGRFKEQKSPESIWTPVPDELVPRPRPGGCAVQGSRFS 377

  Fly   382 ---TLTSIAVNFIKNHPLMEEAVPAVHGRPLLTKVNLHHRLTAIAVHPQVKSLSGAYYD--VIYS 441
               ||....:||||.||||:||||.:..||.:.|..:.::|..:.|..:    :|.:.:  |::.
Zfish   378 TSNTLPDEVLNFIKIHPLMDEAVPLLGHRPWIVKTMVRYQLNTMVVDTE----AGPHRNRTVVFL 438

  Fly   442 GTDDGKVTKFINILSTHPNSTVDRLKTVVISEMQ--------------VLPLGTPIRELVISTSK 492
            |:..|.|.||  :::..|.:......| .:.|::              :.||     .|.:....
Zfish   439 GSTRGTVLKF--LITPSPENQYSNTNT-FLEELEGYNPERCGDDSAQAMQPL-----SLTLDKPS 495

  Fly   493 NSLVVVSDGSLVSVPLHHCSHIVDCL-GCLSLQDPICAWDLQTHECKNLATSQHKFGTKTYLQSL 556
            ::|::.....:|.||:..|.....|: .|::.:||.|.|.              :..|.|.|:
Zfish   496 HTLLLAFHSCVVRVPVARCHLHSRCMKNCIASRDPYCGWT--------------RGSTCTLLR-- 544

  Fly   557 NSTKKAAALLCPHIPRDAPGAETVSFVTMAPPPTEEQKLLYSNVGSSQGNQPSLEQQPTGGDDFG 621
                              ||.. :.||         |.:.|       ||...|      ||..|
Zfish   545 ------------------PGTR-LPFV---------QDVEY-------GNTSHL------GDCDG 568

  Fly   622 LNKITLTSMDPDDIMPNLNDPQKSTASVDEIKYASTPSFMLLTTIVFFTFLVG----GIAGICCV 682
            |  :..:.||..:.:..||                     ||.......|..|    |:| :|.:
Zfish   569 L--LRESFMDEPESLVTLN---------------------LLVVAAVSAFSTGAALSGLA-VCWI 609

  Fly   683 KAKSRLMEAQMDESHRNHFGKPMQFKHQNTGKDINLLMGSN 723
            ..:.        ..||:|...|.....:.:.|: ..:||.:
Zfish   610 MGQK--------HRHRSHSNTPSSSIQRKSEKE-RCMMGQS 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_001163178.1	Sema_1A	55..511	CDD:200498	170/472 (36%)
		PSI	510..>537	CDD:214655	7/27 (26%)
sema6ba	NP_001353244.1	Sema_6B	49..512	CDD:200528	170/470 (36%)
		PSI	513..>542	CDD:307546	8/42 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	318	1.000	Domainoid score	I1228
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	349	1.000	Inparanoid score	I2257
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000892
OrthoInspector	1	1.000	-	-		mtm6502
orthoMCL	1	0.900	-	-		OOG6_101616
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X415
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.960