Protein Alignment Sema1b and si:ch211-113g11.6

DIOPT Version :10

• Sequence 1: NP_611244.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: XP_005158115.1
• Gene: si:ch211-113g11.6 / 559008
• ZFINID: ZDB-GENE-060503-473
• Length: 632
• Species: Danio rerio
• Alignment Length: 587
• Identity: 153/587 - (26%)
• Similarity: 250/587 - (42%)
• Gaps: 114/587 - (19%)

  Fly    19 MILLITLSGLTIVAGWMPDVKPDLQTKQDKVLAHFIGNSTDYFKILD--------HNDE--FVLV 73
            :::|.||..: ::|...|.:|             ||.|.:..|:.:.        |..|  .:.|
Zfish     3 LLVLATLFSV-VLAEKSPRLK-------------FIVNESPRFRFIKPENFTTVYHQQETDVLYV 53

  Fly    74 GAKDVIYNVSLNGLKEI--ARLEWHSTDADRELCALKG---KHEWDCHNYLRVYALRPNGEVLLC 133
            |.:.|||.:|... ||:  .::.....:..:|||..|.   |||  |.|::.|.. :....:::|
Zfish    54 GGQGVIYKLSFRD-KEVHDIQIPVVMDENAKELCHSKSSQWKHE--CDNFITVIE-KVGDSMVVC 114

  Fly   134 GTNSYKPRC----RHYTPVEVSSEEAGSAGHAHAMRYEVSRDVEAQGLCPYSPAHNSTYAFADGH 194
            ||.:..|:|    ...|..::|.|.|.|                 ..|.|: |:..|....||.:
Zfish   115 GTRAGTPKCWLLVNDSTLTDMSEETAAS-----------------NILAPF-PSQRSISLSADEN 161

  Fly   195 LYSATVADFSGGDPLIYR-----ENLRTEQYDLKQLNQPDFVGAI------ERNGYVLFFFRELS 248
            ||||..| .:|....|.|     :.|:||.   |.|..|.|.||.      :....:.|||.|::
Zfish   162 LYSALSA-AAGQTGTIRRTFGSKKQLKTEN---KWLQNPQFAGAAVIPHEEKLKNEIYFFFSEVN 222

  Fly   249 MEVMNFGKAVYSRVARVCKNDRGG-----PYSHGKSWTSFLKARLNCSVPGEFPFYFDEIQAISP 308
            .......:...:|:.|||..|.||     |    .|||:|||||:.|...|. |..::..:....
Zfish   223 SSSSLDEEPYRARIGRVCMVDEGGLQNVLP----NSWTTFLKARVMCGKSGT-PVQYNNFKQAFV 282

  Fly   309 IVESGSKSLIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWLPVEREQVPKPRP 373
            :.......|||.:|:.:.|.   :.|||::::||    |..|.|.|      |......:..|||
Zfish   283 LTSHLRTGLIYGIFSNAWNT---TVVCAYSIEDI----DKAFSSSK------LKGYNSPLANPRP 334

  Fly   374 GQCV--EDSRTLTSIAVNFIKNHPLMEEAVPAVHGRPLLTKVNLHHRLTAIAVHPQVKSLSGAYY 436
            |.|.  .:::......::.|::||.:||.:..||..||...|..|  .|.| |...|.:::..:|
Zfish   335 GTCAFKNNTQAHNQKILSVIRDHPEIEEVIGPVHDVPLELSVQDH--FTHI-VADTVLAVNDEHY 396

  Fly   437 DVIYSGTDDGKVTKFINILSTHPNSTVDRLKTVVISEMQVLPLGTPIRELVISTSKNSLVVVSDG 501
            .:||.||:.|||.|.::.:.          ...:|::..:....:|:..:.|...|..|.:.:..
Zfish   397 SIIYLGTEKGKVLKVLHTIE----------GAFIIAQYSLFHDDSPVTNMAIDPKKGHLYIGTQL 451

  Fly   502 SLVSVPLHHCSHI-VDCLGCLSLQDPICAWDLQTHECKNLATSQHKFGTKTYLQSLNSTKKAAAL 565
            .:..:||..|... :.|..|:..:||.||||:...:|..:.|.  ...|.:.:|:|:.:.   |.
Zfish   452 EVQRLPLADCGRYGLSCRECILSRDPYCAWDVHKKKCTAITTG--SINTGSLIQTLDHSN---AS 511

  Fly   566 LC 567
            :|
Zfish   512 IC 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_611244.1	Sema_1A	55..511	CDD:200498	129/492 (26%)
		PSI	510..>537	CDD:214655	9/27 (33%)
si:ch211-113g11.6	XP_005158115.1	Sema	37..459	CDD:472829	126/478 (26%)
		PSI	460..>490	CDD:214655	10/29 (34%)
		Ig	537..604	CDD:472250
		Ig strand B	537..541	CDD:409353
		Ig strand C	549..553	CDD:409353
		Ig strand E	569..573	CDD:409353
		Ig strand F	584..589	CDD:409353
		Ig strand G	601..604	CDD:409353