Protein Alignment Sema1b and sema6cb

DIOPT Version :10

• Sequence 1: NP_611244.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: XP_073781138.1
• Gene: sema6cb / 556743
• ZFINID: ZDB-GENE-040724-119
• Length: 1105
• Species: Danio rerio
• Alignment Length: 868
• Identity: 257/868 - (29%)
• Similarity: 398/868 - (45%)
• Gaps: 195/868 - (22%)

  Fly     5 SRPSSAAMLVNAIPMILLITLSGLT-IVAGWMP---DVKP--DLQTKQDKVLAHFIGNSTDY--- 60
            |||        .:.:.|::||:.|. :..|..|   |::|  .:.::...:...|.||.:|.
Zfish    49 SRP--------LLALTLMLTLTCLKHLCHGATPFPQDLEPIRTVGSEHTYLYPSFQGNMSDNDTA 105

  Fly    61 -----FKILDHNDEFVLVGAKDVIYNVSLN-GLKEIA---RLEWHSTDADRELCALKGKHEWDCH 116
                 |:.:...:..|.:.|:|.::.::|: .|:.|.   :|.|.:.|.::  |.::||:..:|:
Zfish   106 RLGLDFQRMLRINHMVYIAARDHVFAINLSASLERIVPQQKLTWKTKDVEK--CTVRGKNSDECY 168

  Fly   117 NYLRVYALRPNGEVLLCGTNSYKPRCRHYTPVEVSSEEAGSAGHAHAMRYEVSRDVEAQGLCPYS 181
            ||::|...|.:..:..||||::.|.||:|   ::||.|            :...:|..|..||:.
Zfish   169 NYIKVLVPRNDETLFACGTNAFNPTCRNY---KMSSLE------------QDGEEVIGQARCPFE 218

  Fly   182 PAHNSTYAFADGHLYSATVADFSGGDPLIYRE------NLRTEQYDLKQLNQPDFVGAIERNGYV 240
            ...::...||.|..||||:.||...|.:|||.      .|||.:||.|.|.:|.|:.|||...||
Zfish   219 SRQSNVGLFAGGDFYSATMTDFLASDAVIYRSLGESSPVLRTVKYDSKWLREPHFLHAIEYGNYV 283

  Fly   241 LFFFRELSMEVMNFGKAVYSRVARVCKNDRGG-PYSHGKSWTSFLKARLNCSVPGEFPFYFDEIQ 304
            .||..|:::|....||.|:||||||||||.|| |....:.|||||||||||||||:..||||.:|
Zfish   284 YFFLSEIAVEYTTLGKVVFSRVARVCKNDNGGSPRVLERYWTSFLKARLNCSVPGDSFFYFDVLQ 348

  Fly   305 AISPIVESGSKSLIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWLPVEREQVP 369
            :::.:::...:..:..||||..|:|.|||||||.:|||...|:|:||.|::|:|.|.||..|.||
Zfish   349 SLTNVMQINHRPAVLGVFTTQANSITGSAVCAFYMDDIEKVFNGKFKEQRNSESAWTPVPDEAVP 413

  Fly   370 KPRPGQCVED--------SRTLTSIAVNFIKNHPLMEEAVPAVHGRPLLTKVNLHHRLTAIAVHP 426
            |||||.|..|        |.......:.|||::|||:||||:|:.||..|:.....:||.||
Zfish   414 KPRPGSCAGDGPAAGYKSSTNFPDETLTFIKSYPLMDEAVPSVNNRPCFTRTTSRFKLTQIA--- 475

  Fly   427 QVKSLSGAY--YDVIYSGTDDGKVTKFINILSTHPNSTVDRLKTVVISEMQVL-PLGTPIR---- 484
             |.:.:|.|  |.|::.|:::|.|.|.  :.|.||||:   ..|.|:.::.|. |....:|
Zfish   476 -VDTAAGPYKNYTVVFLGSENGHVLKV--LASMHPNSS---YSTQVLEDIDVYNPNKCNVRGEDR 534

  Fly   485 ---ELVISTSKNSLVVVSDGSLVSVPLHHCSHIVDC-LGCLSLQDPICAWDLQTHECKNLATSQH 545
               .|.:....::|.|...|.::.|||..||....| ..|||.:||.|.| |....|..:|.. .
Zfish   535 RILGLELDKDHHALFVAFTGCVIRVPLSRCSDYGICRKSCLSSRDPYCIW-LSAGNCATVAPG-F 597

  Fly   546 KFGTKTYLQS------------LNSTKKAAALLCPHIPRDAP-GAETVSFVTMAPPPT----EEQ 593
            |.|.:.|::|            |.:|:|....:.....:.:| .|.|.:......|.|    ||.
Zfish   598 KSGFEQYVESGYPQYPDSCHDVLATTRKQNPAVDSAYGKTSPTSASTTNQGPAGAPETGTHPEEG 662

  Fly   594 KLLYSNVGSSQGNQPSLEQQPTGGDDFGLNKITLTSMDPDDIMPNLNDPQKSTASVDEIKYASTP 658
            :         :|.|.|.:.:|...:..|:.:       |.::       .||..||
Zfish   663 R---------RGGQGSPDLEPGSVEMEGVRR-------PPEV-------DKSNHSV--------- 695

  Fly   659 SFMLLTTIVFFTFLVGG-IAG--ICCV------KAK----------------------SRLMEAQ 692
            .:.||...|...|::|. ::|  :.|.      |.|                      :.|:|:|
Zfish   696 HYTLLIACVLVAFVLGAFLSGFLVSCYCNHNVNKTKRLSKDPEAPIPHALSLRSLAKLNGLLESQ 760

  Fly   693 ---------------------MDESHRN--HFGKPMQFKHQNTGKDINLLMGSNAYTTTQKTPNL 734
                                 .:::||.  |.....:..|.:......|    :...|...||.|
Zfish   761 NKDEKLEVSSPKLYNSFFANGKEQAHRRNAHHAAMTELIHPHHHHSAEL----SGLPTPDSTPEL 821

  Fly   735 DLEK--------DRSHECKNSTE 749
            .::.        :::..|.|:.|
Zfish   822 PIKSMKAFKNQWEKNQNCNNAKE 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_611244.1	Sema_1A	55..511	CDD:200498	184/492 (37%)
		PSI	510..>537	CDD:214655	11/27 (41%)
sema6cb	XP_073781138.1	None