Protein Alignment Sema1b and Sema7a

DIOPT Version :9

• Sequence 1: NP_001163178.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_001101623.1
• Gene: Sema7a / 315711
• RGDID: 1305192
• Length: 666
• Species: Rattus norvegicus
• Alignment Length: 643
• Identity: 157/643 - (24%)
• Similarity: 257/643 - (39%)
• Gaps: 157/643 - (24%)

  Fly     4 KSRPSSAAMLVNAIP---------MILLI-----------TLSGLTIVAGWMPDVKPDL-QTKQD 47
            ::.||:....|.::|         .:||:           :.||..|.|.|......|. |.:..
  Rat     8 RAAPSAPRARVLSLPARFGLPLRLRLLLVFWVTAASAQGHSRSGPRISAVWKGQDHVDFGQPEPH 72

  Fly    48 KVLAHFIGNSTDYFKILDHNDEFVLVGAKDVIY--------NVSLNGLKEIARLEWHSTDADREL 104
            .||.|..|:.:            |.||.:..:|        |.|:..:               .:
  Rat    73 NVLFHEPGSFS------------VWVGGRGKVYLFNFPEGKNASVRTV---------------NI 110

  Fly   105 CALKG--KHEWDCHNYLRVYALRPNGEVLLCGTNSYKPRCRHYTPVEVSSEEAGSAGHAHAMRYE 167
            .:.||  :.:.||.||:.:...|.|| :|:||||:.||.|.:.    |:.....|.|
  Rat   111 GSTKGSCQDKQDCENYITLLERRGNG-LLVCGTNARKPSCWNL----VNDSVVMSLG-------- 162

  Fly   168 VSRDVEAQGLCPYSPAHNSTYAFADGHLYSATV--ADFSGGDPLIYRENLRTEQYDLKQLNQ-PD 229
                 |.:|..|:||..||...|....:|| |:  .:::|..|...|....:|.|....:.| |.
  Rat   163 -----EMKGYAPFSPDENSLVLFEGDEVYS-TIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQ 221

  Fly   230 FVGAI---ERNGY---VLFFFRELSMEVMNFGKAVYSRVARVCKNDRGGPYSHGKS-WTSFLKAR 287
            |:.|.   :...|   :.:||||.:.:.........||||::|:.|:||..|...| |.:||||.
  Rat   222 FIKATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAM 286

  Fly   288 LNCSVPGEFPFYFDEIQAISPIVESGSK---SLIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGE 349
            |.|| .......|:.:|.:..:.:...:   :.:|.||:...|.   ||||.:::.||    |..
  Rat   287 LVCS-DAATNRNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDI----DRV 343

  Fly   350 FKSQKDSQSHWLPVEREQVPKPRPGQCVEDSRTLTSIAVNFIKNHPLMEEAV--------PAVHG 406
            |::......|.      .:|.||||.|:...:.:.:.......:||.:.:.|        |..|.
  Rat   344 FRTSSLKGYHM------GLPNPRPGMCLPKKQPIPTETFQVADSHPEVAQRVEPMGPLKTPLFHS 402

  Fly   407 RPLLTKVNLHHRLTAIAVHPQVKSLSGAYYDVIYSGTDDGKVTKFINILSTHPNSTVDRLKTVVI 471
            :....||.:|          ::::.:|..:.|:|..||.|.:.|.:        .:.|:..:.|.
  Rat   403 KYHYQKVVVH----------RMQASNGETFHVLYLTTDRGTIHKVV--------ESGDQEHSFVF 449

  Fly   472 SEMQVLPL--GTPIRELVISTSKNSLVVVSDGSLVSVPLHHCS-HIVDCLGCLSLQDPICAWDLQ 533
            :.|::.|.  ...|:.:.:...:..|.|.|...:..|||..|. :...|.|||..:||.|.||..
  Rat   450 NIMEIQPFHRAAAIQAISLDADRRKLYVTSPWEVSQVPLDMCGVYSGGCHGCLMSRDPYCGWDQD 514

  Fly   534 THECKNLATSQHKFGTKTYLQSLNSTKKAAALLCPHIPRDAPGAETVSFVTMAPPPTE 591
            ...|.::.:||     ::.|||:|..:       ||  |:.|.          |.|.|
  Rat   515 QDRCVSIYSSQ-----RSVLQSINPAE-------PH--RECPN----------PNPDE 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_001163178.1	Sema_1A	55..511	CDD:200498	117/488 (24%)
		PSI	510..>537	CDD:214655	10/27 (37%)
Sema7a	NP_001101623.1	PSI	491..>520	CDD:279745	11/28 (39%)
		Ig	549..622	CDD:299845	157/643 (24%)
		Sema_7A	70..489	CDD:200504	119/496 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000