Protein Alignment Sema1b and Sema6d

DIOPT Version :10

• Sequence 1: NP_611244.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: XP_063139809.1
• Gene: Sema6d / 311384
• RGDID: 1310910
• Length: 1106
• Species: Rattus norvegicus
• Alignment Length: 822
• Identity: 263/822 - (31%)
• Similarity: 386/822 - (46%)
• Gaps: 143/822 - (17%)

  Fly     5 SRPSSAAMLVNAIPMILLITLSGLTIVAGWMPDVKPDLQTKQDKVLAHF-----------IGNST 58
            |||:....|:....:.||:  |.|..|:  .|:....|.|    |..|:           .||.:
  Rat    17 SRPTMRFFLLWFCVLFLLV--SRLRAVS--FPEDDEPLNT----VDYHYSRQYPVFRGRPSGNES 73

  Fly    59 ----DYFKILDHNDEFVLVGAKDVIYNVSLNGLKEI-----ARLEWHSTDADRELCALKGKHEWD 114
                |:..:|...|...:.| :|.:|.|:||.:.:.     .:|.|.|...|||.||:||||:.:
  Rat    74 QHRLDFQLMLKIRDTLYIAG-RDQVYTVNLNDIPQTEVIPSKKLTWRSRQQDRENCAMKGKHKDE 137

  Fly   115 CHNYLRVYALRPNGEVLLCGTNSYKPRCRHY--TPVEVSSEEAGSAGHAHAMRYEVSRDVEAQGL 177
            |||:::|:..|.:..|.:||||::.|.||:|  :.:|...||                 :.....
  Rat   138 CHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEE-----------------ISGLAR 185

  Fly   178 CPYSPAHNSTYAFADGHLYSATVADFSGGDPLIYR-----ENLRTEQYDLKQLNQPDFVGAIERN 237
            ||:.....:...||||.|||||||||...|.:|||     ..|||.:||.|.:.:|.|:.|||..
  Rat   186 CPFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIKEPHFLHAIEYG 250

  Fly   238 GYVLFFFRELSMEVMNFGKAVYSRVARVCKNDRGGPYS-HGKSWTSFLKARLNCSVPGEFPFYFD 301
            .||.|||||:::|..|.||||||||||:||||.||... ..|.|||||||||||||||:..||||
  Rat   251 NYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSFFYFD 315

  Fly   302 EIQAISPIVESGSKSLIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWLPVERE 366
            .:|:|:.|::......:..||||.:|:|||||||||::|||...|.|.||.||...|.|..|..:
  Rat   316 VLQSITDIIQINGIPTVIGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVWTAVPED 380

  Fly   367 QVPKPRPGQCVEDSRT---LTSI-----AVNFIKNHPLMEEAVPAVHGRPLLTKVNLHHRLTAIA 423
            :|||||||.|.:....   .|||     .::|||:||||:.|||.:...|..||..:.:|||||
  Rat   381 KVPKPRPGCCAKHGLAEAYKTSIDFPDDTLSFIKSHPLMDSAVPPIADEPWFTKTRVRYRLTAI- 444

  Fly   424 VHPQVKSLSGAY--YDVIYSGTDDGKVTKFINILSTHPNSTVDRLKTVVISEMQVLPLGTPIR-- 484
               :|...:|.|  |.||:.|::.|.|.|.  :..|.|.|..|   :|::.|::..   .|.:
  Rat   445 ---EVDRSAGPYQNYTVIFVGSEAGVVLKV--LAKTSPFSLND---SVLLEEIEAY---NPAKCS 498

  Fly   485 ----------ELVISTSKNSLVVVSDGSLVSVPLHHCSHIVDC-LGCLSLQDPICAWDLQTHECK 538
                      .|.:....::|.|.....:|.:||..|.....| ..|::.:||.|.| |....|:
  Rat   499 AESEEDRKVVSLQLDRDHHALYVAFSSCVVRIPLSRCERYGSCKKSCIASRDPYCGW-LSQGVCE 562

  Fly   539 NLATSQ----------HKFGTKTYLQSLNSTKKAAALLCPHIPRDAPGAETVSFVTMAPPPTEEQ 593
            .:....          |......|.|.......|....| |  ...|.:.|..:.... .||.:.
  Rat   563 RVTLGMLLLTEDFFAFHNHSAGGYEQDTEYGNTAHLGDC-H--ESLPTSTTPDYKIFG-GPTSDM 623

  Fly   594 KLLYSNVGSSQGNQPSLEQQPTGGDDFGLNKITLTS--MDPDDIMPNLNDPQKSTASVD-----E 651
            ::..|:| ::..:.|.:..:..   |....|:|.:.  :..||  ||.:|...:.:.:.     |
  Rat   624 EVPSSSV-TTVASSPEITSKVI---DTWRPKLTSSRKFVVQDD--PNTSDFTDTISGIPKGVRWE 682

  Fly   652 IKYASTPSFM---LLTTIVFFTFLVGG-IAGIC--CVK----AKSRLMEAQMDESH--------- 697
            ::...:...:   :|.|.||..|::|. |||:.  |.:    .|:|.:....:.:.
  Rat   683 VQSGDSNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDSSGSF 747

  Fly   698 ---RNHFGKPMQFKHQNTGKDINLLMGSNAYTTTQK-TPNLD 735
               ...|..|::...||....   .:.||..|:.:: .||.|
  Rat   748 AKLNGLFDSPVKEYQQNIDSP---KLYSNLLTSRKELPPNTD 786

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_611244.1	Sema_1A	55..511	CDD:200498	196/494 (40%)
		PSI	510..>537	CDD:214655	8/27 (30%)
Sema6d	XP_063139809.1	None