Protein Alignment Sema1b and Sema3c

DIOPT Version :10

• Sequence 1: NP_611244.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_001426780.1
• Gene: Sema3c / 296787
• RGDID: 1309343
• Length: 754
• Species: Rattus norvegicus
• Alignment Length: 565
• Identity: 165/565 - (29%)
• Similarity: 281/565 - (49%)
• Gaps: 65/565 - (11%)

  Fly    12 MLVNAIPMILLITLSGLTIVAGWMPDVKPDL------QTKQDKV--LAHFIGNSTDY-FKILDHN 67
            |.:..|.:::.:.:..:.:.....|..:..|      :||..:.  |:|   ...|| ..::|.:
  Rat     1 MALREICVLVGVFICSICVQGSSQPQARVYLTFDELRETKTSEYFSLSH---QQLDYRILLMDED 62

  Fly    68 DEFVLVGAKDVIYNVSLNGL-KEIARLEWHSTDADRELCALKGK---HEWDCHNYLRVYALRPNG 128
            .:.:.||:||.|.::::|.: :|...:.|.::....|.|.:.||   |  .|.|::||.......
  Rat    63 QDRIYVGSKDHILSLNINNISQEPLSVFWPASTIKVEECKMAGKDPTH--GCGNFVRVIQTFNRT 125

  Fly   129 EVLLCGTNSYKPRCRHYTPVEVSSEEAGSAGHAHAMRYEVSRDVEA-QGLCPYSPAHNSTYAFAD 192
            .:.:||:.::.|.|.:......|.::.          :.:....|: :|.|.::|..|:.....:
  Rat   126 HLYVCGSGAFSPVCTYLNRGRRSEDQV----------FMIDSKCESGKGRCSFNPNVNTVSVMIN 180

  Fly   193 GHLYSATVADFSGGDPLIY-----RENLRTEQYDLKQLNQPDFV-------GAIERNGYVLFFFR 245
            ..|:|....||.|.|..|:     |..:||:|::.|.|::|.||       |....:..|.|||:
  Rat   181 EELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFK 245

  Fly   246 ELSMEVMNFGKAVYSRVARVCKNDRGGPYSHGKSWTSFLKARLNCSVPGEF--PFYFDEIQAISP 308
            |...:.....|.::|.|||:|.||.||..|....||:||||||.|||..|.  ..:|||::.:..
  Rat   246 ERLTDNNRSTKQIHSMVARICPNDTGGQRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFL 310

  Fly   309 I-VESGSKSLIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWLPVEREQVPKPR 372
            : .::...:|:|.:||||.:...|||||.:::.||...|:|.| :.|:..:|.|...:.::|.||
  Rat   311 LETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPF-AHKEGPNHQLISYQGRIPYPR 374

  Fly   373 PGQC--------VEDSRTLTSIAVNFIKNHPLMEEAVPAVHGRPLLTKVNLHHRLTAIAVHPQVK 429
            ||.|        :..::......|.||:|||||..::..:|.|||:.::...::.|.||| .:|.
  Rat   375 PGTCPGGAFTPNMRTTKDFPDDVVTFIRNHPLMYNSIYPIHRRPLIVRIGTDYKYTKIAV-DRVN 438

  Fly   430 SLSGAYYDVIYSGTDDGKVTKFINILSTHPNSTVDRLKTVVISEMQVLPLGTPIRELVISTSKNS 494
            :..|.|: |::.|||.|.|.|.: :|.|:.:::.:    :::.|::|.....||..:.||:.|..
  Rat   439 AADGRYH-VLFLGTDRGTVQKVV-VLPTNSSASGE----LILEELEVFKNHVPITTMKISSKKQQ 497

  Fly   495 LVVVSDGSLVSVPLHHCSHI--VDCLGCLSLQDPICAWDLQTHEC 537
            |.|.|:..:..|.||.| ||  ..|..|...:||.||||  .|.|
  Rat   498 LYVSSNEGVSQVSLHRC-HIYGTACADCCLARDPYCAWD--GHSC 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_611244.1	Sema_1A	55..511	CDD:200498	144/484 (30%)
		PSI	510..>537	CDD:214655	12/28 (43%)
Sema3c	NP_001426780.1	None