Protein Alignment Sema1b and Sema2b

DIOPT Version :9

• Sequence 1: NP_001163178.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_001261024.1
• Gene: Sema2b / 246538
• FlyBaseID: FBgn0264273
• Length: 824
• Species: Drosophila melanogaster
• Alignment Length: 628
• Identity: 210/628 - (33%)
• Similarity: 316/628 - (50%)
• Gaps: 114/628 - (18%)

  Fly    64 LDHNDEFVLVGAKDVIYNVSLNGL------KEIARLEWHSTDADRELCALKGKHE-WDCHNYLRV 121
            :|..:..:.|||.|.|:.::|..:      :::..||  .|.:|...|..|||.| .:|.|::||
  Fly   127 MDERNNALYVGAMDRIFRLNLRNISQSICERDVLILE--PTGSDILNCVSKGKREKVECRNHIRV 189

  Fly   122 YALRP---NGEVL-LCGTNSYKPRCRHYTPVEVSSEEAGSAGHAHAMRYEVSRDVEAQGL----C 178
              ::|   ||:.| :||||::.|:           :...:|...|..|   |:.|...||    |
  Fly   190 --IQPMNFNGQKLYVCGTNAHNPK-----------DYVINANLTHLPR---SQYVPGIGLGIGKC 238

  Fly   179 PYSPAHNSTYAFADG-------HLYSATVADFSGGDPLIYRENL-------------RTEQYDLK 223
            ||.||.|||..:.:.       .||:.|.|:|:..|.:|:|.:|             ||.:||.|
  Fly   239 PYDPADNSTAVYVENGNPFGLPALYAGTNAEFTKADSVIFRSDLYNLTNGRKEANFKRTVKYDSK 303

  Fly   224 QLNQPDFVGAIERNGYVLFFFRELSMEVMNFGKAVYSRVARVCKNDRGGPYSHGKSWTSFLKARL 288
            .|::|:|||:.|...:|.|||||.::|.:|.||||||||||||||||||.|...::|.::||||:
  Fly   304 LLDKPNFVGSFEIGEFVYFFFREHAVEYINCGKAVYSRVARVCKNDRGGKYMISQNWATYLKARM 368

  Fly   289 NCSVPGEFPFYFDEIQAISPIVESGSKSLIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQ 353
            |||:..||||||:|||::..:....:|  .||.|||:.|.:.|||||::::.||.|||||:||.|
  Fly   369 NCSISSEFPFYFNEIQSVYKMPTDDTK--FYATFTTNTNGLIGSAVCSYDIRDINAAFDGKFKEQ 431

  Fly   354 KDSQSHWLPVEREQVPKPRPGQCVEDSRTLTSIAVNFIKNHPLMEEAVPAVHGRPLLTKVNLHHR 418
            ..|.|.||||...:||:||||.|..|:.||....:|||:.||||::||....|.|:..|.::  .
  Fly   432 ATSNSAWLPVLNSKVPEPRPGTCHNDTATLPDSVLNFIRKHPLMDKAVDHEFGNPVFFKRDV--I 494

  Fly   419 LTAIAVHP-QVKSLSGAYYDVIYSGTDDG---KVTKFINILSTHPNSTVDRLKTVVISEMQVLPL 479
            ||.:.|.. ::..|:..:. |.:..|..|   |:.:|::....|.|         ::...:..|.
  Fly   495 LTKLVVDKIRIDKLNQEFL-VYFVATTSGHIYKIVQFMHYGQRHSN---------LVDIFEASPH 549

  Fly   480 GTPIRELVISTSKNSLVVVSDGSLVSVPLHHCSHIVD-CLGCLSLQDPICAWDLQTHECK--NLA 541
            ..||||:.:|....||.|.:|..:..:.:..|:...| |..|:|  ||.|.||...:.|:  .|.
  Fly   550 SEPIREMTLSHKTGSLYVATDHQVKQIDIAMCARRYDSCFRCVS--DPYCGWDKDVNACRPYQLG 612

  Fly   542 TSQ---------------HKFGTKTYLQSLNSTKKAAALLCPHIPRDAPGAETVSFVTMAPPPTE 591
            ..|               .|..|.:|.|:|:       |.|              ||.|.....:
  Fly   613 LLQDVANETSGICDTSVLRKKVTSSYGQTLH-------LSC--------------FVKMPEVLRK 656

  Fly   592 EQKLLYSNVGSSQGNQPSLEQQPTGGDDFGLNKITLTSMDPDD 634
            :|...|.:  |::..:..:...||...|.....:.|.:::..|
  Fly   657 KQTRWYHH--STEKGRYEVRYTPTKYIDTNEGGLVLLAVNEGD 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_001163178.1	Sema_1A	55..511	CDD:200498	179/485 (37%)
		PSI	510..>537	CDD:214655	10/27 (37%)
Sema2b	NP_001261024.1	Sema_2A	120..579	CDD:200499	179/483 (37%)
		Ig	632..720	CDD:299845	18/89 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910