Protein Alignment Sema1b and Sema3g

DIOPT Version :9

• Sequence 1: NP_001163178.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_001020550.1
• Gene: Sema3g / 218877
• MGIID: 3041242
• Length: 780
• Species: Mus musculus
• Alignment Length: 576
• Identity: 181/576 - (31%)
• Similarity: 265/576 - (46%)
• Gaps: 103/576 - (17%)

  Fly    64 LDHNDEFVLVGAKDVIYNVSLNGL----KEIARLEWHSTDADRELCALKGKHE-WDCHNYLRVYA 123
            ||...:.:.:|::|.:|::.|:..    :|:.   |......:..|..|||.. .:|.|::||
Mouse    63 LDEYRDRLFLGSRDALYSLRLDQAWPDPREVL---WLPQPGQKVECVRKGKDPLTECANFVRV-- 122

  Fly   124 LRPNG--EVLLCGTNSYKPRCRHYTPVEVSSEEAGSAGH--AHAMRYEVSRDVEAQGLCPYSPAH 184
            |:|:.  .:|.|||.:::|.|...|           .||  .|.:|.:.|.....:|.||:.|:.
Mouse   123 LQPHNRTHLLACGTGAFQPICTFIT-----------VGHRGEHVLRLDASSVENGRGRCPHEPSR 176

  Fly   185 NSTYAFADGHLYSATVADFSGGDPLIYREN-----LRTEQYDLKQLNQPDFVGA--IERNG---- 238
            .....|..|.||:...|||.|.:.:|:|..     ||::. |...|::|.||.|  |..|.
Mouse   177 PFASTFVGGELYTGLTADFLGREAMIFRSGGPRPALRSDS-DQSLLHEPRFVMAARIPDNSDRDD 240

  Fly   239 -YVLFFFRE-LSMEVMNFGKAVYSRVARVCKNDRGGPYSHGKSWTSFLKARLNCSVPGE--FPFY 299
             .|.|||.| :.......|....|||.|||.||.||.......|::||||||.|||||.  ...:
Mouse   241 DKVYFFFSETVPSPDGGPGHVTISRVGRVCVNDAGGQRVLVNKWSTFLKARLVCSVPGPGGAETH 305

  Fly   300 FDEIQAISPIVESGSKSL-IYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWLPV 363
            ||:::.:..:.....||| :||:|:|......|.|||.:::.||...|:|.|..:...|..|.|.
Mouse   306 FDQLEDVFLLWPKAGKSLEVYALFSTVSAVFQGFAVCVYHMVDIWEVFNGPFAHRDGPQHQWGPY 370

  Fly   364 EREQVPKPRPGQC-----VEDSRTLTSI------AVNFIKNHPLMEEAVPAVHGRPLLTKVNLHH 417
             ..:||.||||.|     .:..|...|.      .:.|:::||||.:.|....|||:|.|.:|..
Mouse   371 -GGKVPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFVRDHPLMFQPVRPRRGRPVLVKTHLAQ 434

  Fly   418 RLTAIAVHPQVKSLSGAYYDVIYSGTDDGKVTKFINILS---THPNSTVDRLKTVVISEMQVLPL 479
            ||..|.| .:|::..|. ||||:.|||.|.|.|.|.:..   |.|       :.||:.|:||..:
Mouse   435 RLRQIVV-DRVEAEDGT-YDVIFLGTDSGSVLKVIALQGGGLTEP-------EEVVLEELQVFKV 490

  Fly   480 GTPIRELVISTSKNSLVVVSDGSLVSVPLHHC-SHIVDCLGCLSLQDPICAWDLQT--------- 534
            .|||.|:.||..:.:|.|.|...:..:.||.| ::...|..|...:||.||||...
Mouse   491 PTPITEMEISVKRQTLYVGSPLGVARLQLHQCETYGSACAECCLARDPYCAWDGTACARYRPSSG 555

  Fly   535 ----------H-----ECKNLATSQHK---------FGTK---TYLQSLNSTKKAA 563
                      |     :|.....||:|         |||:   |:|:.|..:.:||
Mouse   556 KRRFRRQDIRHGNPAVQCLGQGQSQNKAASGLMTRVFGTEHNSTFLECLPKSPQAA 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_001163178.1	Sema_1A	55..511	CDD:200498	159/485 (33%)
		PSI	510..>537	CDD:214655	10/51 (20%)
Sema3g	NP_001020550.1	Sema	49..522	CDD:301699	159/485 (33%)
		PSI	521..567	CDD:214655	9/45 (20%)
		Ig_Semaphorin_classIII	591..676	CDD:143279	8/21 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910