Protein Alignment Sema1b and Sema7a

DIOPT Version :9

• Sequence 1: NP_001163178.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_035482.1
• Gene: Sema7a / 20361
• MGIID: 1306826
• Length: 664
• Species: Mus musculus
• Alignment Length: 633
• Identity: 156/633 - (24%)
• Similarity: 258/633 - (40%)
• Gaps: 139/633 - (21%)

  Fly     4 KSRPSSAAMLVNAIP---------MILLI-----------TLSGLTIVAGWMPDVKPDL-QTKQD 47
            ::.||:....|.::|         .:||:           :.||..|.|.|......|. |.:..
Mouse     8 RAAPSAPRARVLSLPARFGLPLRLRLLLVFWVAAASAQGHSRSGPRISAVWKGQDHVDFSQPEPH 72

  Fly    48 KVLAHFIGNSTDYFKILDHNDEFVLVGAKDVIYNVSLNGLKEIARLEWHSTDADRELCALKGKHE 112
            .||.|..|:.:            |.||.:..:|:.:....|. |.:...:..:.:..|    :.:
Mouse    73 TVLFHEPGSFS------------VWVGGRGKVYHFNFPEGKN-ASVRTVNIGSTKGSC----QDK 120

  Fly   113 WDCHNYLRVYALRPNGEVLLCGTNSYKPRCRHYTPVEVSSEEAGSAGHAHAMRYEVSRDVEAQGL 177
            .||.||:.:...|.|| :|:||||:.||.|.:.    |:.....|.|             |.:|.
Mouse   121 QDCGNYITLLERRGNG-LLVCGTNARKPSCWNL----VNDSVVMSLG-------------EMKGY 167

  Fly   178 CPYSPAHNSTYAFADGHLYSATV--ADFSGGDPLIYRENLRTEQYDLKQLNQ-PDFVGAI---ER 236
            .|:||..||...|....:|| |:  .:::|..|...|....:|.|....:.| |.|:.|.   :.
Mouse   168 APFSPDENSLVLFEGDEVYS-TIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQD 231

  Fly   237 NGY---VLFFFRELSMEVMNFGKAVYSRVARVCKNDRGGPYSHGKS-WTSFLKARLNCSVPGEFP 297
            ..|   :.:||||.:.:.........||||::|:.|:||..|...| |.:||||.|.|| .....
Mouse   232 QAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCS-DAATN 295

  Fly   298 FYFDEIQAISPIVESGSK---SLIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSH 359
            ..|:.:|.:..:.:...:   :.:|.||:...|.   ||||.:::.||    |..|::......|
Mouse   296 RNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDI----DRVFRTSSLKGYH 353

  Fly   360 WLPVEREQVPKPRPGQCVEDSRTLTSIAVNFIKNHPLMEEAV--------PAVHGRPLLTKVNLH 416
            .      .:|.||||.|:...:.:.:.......:||.:.:.|        |..|.:....||.:|
Mouse   354 M------GLPNPRPGMCLPKKQPIPTETFQVADSHPEVAQRVEPMGPLKTPLFHSKYHYQKVVVH 412

  Fly   417 HRLTAIAVHPQVKSLSGAYYDVIYSGTDDGKVTKFINILSTHPNSTVDRLKTVVISEMQVLPL-- 479
                      ::::.:|..:.|:|..||.|.:.|.:        .:.|:..:.|.:.|::.|.
Mouse   413 ----------RMQASNGETFHVLYLTTDRGTIHKVV--------ESGDQDHSFVFNIMEIQPFHR 459

  Fly   480 GTPIRELVISTSKNSLVVVSDGSLVSVPLHHCS-HIVDCLGCLSLQDPICAWDLQTHECKNLATS 543
            ...|:.:.:...:..|.|.|...:..|||..|. :...|.|||..:||.|.||  ...|.::.:|
Mouse   460 AAAIQAISLDADRRKLYVTSQWEVSQVPLDMCEVYSGGCHGCLMSRDPYCGWD--QDRCVSIYSS 522

  Fly   544 QHKFGTKTYLQSLNSTKKAAALLCPHIPRDAPGAETVSFVTMAPPPTE 591
            |     ::.|||:|..:       ||  |:.|.          |.|.|
Mouse   523 Q-----RSVLQSINPAE-------PH--RECPN----------PKPDE 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_001163178.1	Sema_1A	55..511	CDD:200498	116/478 (24%)
		PSI	510..>537	CDD:214655	10/27 (37%)
Sema7a	NP_035482.1	Sema_7A	70..489	CDD:200504	118/486 (24%)
		Cell attachment site. /evidence=ECO:0000255	265..267		0/1 (0%)
		Interaction with integrins. /evidence=ECO:0000250	265..267		0/1 (0%)
		PSI	491..>518	CDD:279745	11/28 (39%)
		Ig	547..617	CDD:299845	156/633 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000