Protein Alignment Sema1b and Sema5b

DIOPT Version :9

• Sequence 1: NP_001163178.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: XP_006521932.1
• Gene: Sema5b / 20357
• MGIID: 107555
• Length: 1122
• Species: Mus musculus
• Alignment Length: 595
• Identity: 207/595 - (34%)
• Similarity: 308/595 - (51%)
• Gaps: 88/595 - (14%)

  Fly    18 PMILLITLSGLTIVAGWM---PDVKPDLQTKQD------------KVLAHFIGNST-----DYFK 62
            |:.|.:.||.||::...:   .|:..:..::|.            :.|..::.|.|     |:.:
Mouse     6 PLALSLLLSSLTLLVSHLSSSQDIASESSSEQQMCTRREHPIVAFEDLKPWVFNFTYPGVRDFSQ 70

  Fly    63 I-LDHNDEFVLVGAKDVIYNVSLNGLKEIARLEWHSTDADRELCALKGKHEWDCHNYLRVYALRP 126
            : ||.:...::|||::.::.:||..:..:...||.|::..|..|..|||.|.:|.||:||..: .
Mouse    71 LALDPSRNQLIVGARNYLFRLSLANVSLLQATEWASSEDTRRSCQSKGKTEEECQNYVRVLIV-S 134

  Fly   127 NGEVLLCGTNSYKPRCRHYTPVEVSSEEAGSAGHAHAMRYEVSRDVE-AQGL--CPYSPAHNSTY 188
            ..:|.:||||::.|.|        ||.:.|:          :||.:| ..|:  |||.|.||||.
Mouse   135 GRKVFMCGTNAFSPVC--------SSRQVGN----------LSRTIEKINGVARCPYDPRHNSTA 181

  Fly   189 AF-ADGHLYSATVADFSGGDPLIYRE-----NLRTEQYDLKQLNQPDFVGAIERNGYVLFFFREL 247
            .. :.|.||:|||.||||.||.|||.     .|||.||:.|.||:|:||.|.:...:..||.||.
Mouse   182 VISSQGELYAATVIDFSGRDPAIYRSLGSGPPLRTAQYNSKWLNEPNFVAAFDIGLFAYFFLREN 246

  Fly   248 SMEVMNFGKAVYSRVARVCKNDRGGPYSHGKSWTSFLKARLNCSVPGEFPFYFDEIQAISPIVES 312
            ::| .:.|:.||||||||||||.||.:....:||:|:|||||||.|||.|||::|:|:...:.|
Mouse   247 AVE-HDCGRTVYSRVARVCKNDVGGRFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSAFHLPE- 309

  Fly   313 GSKSLIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWLPVEREQVPKPRPGQCV 377
              :.|||.||||:||:|..|||||||:..|..||:|.|:.|::.::.|||: ...:|..:.|...
Mouse   310 --QDLIYGVFTTNVNSIAASAVCAFNLSAISKAFNGPFRYQENPRAAWLPI-ANPIPNFQCGTLP 371

  Fly   378 E--DSRTLTSIAVNFIKNHPLMEEAVPAVHGRPLLTK--VNLHHRLTAIAVHPQVKSLSGAYYDV 438
            |  .:..||..::...:...||.|||..|...|.:|:  |...|.:..:.   |.|.   ..|.|
Mouse   372 ETGPNENLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVRFSHLVVDLV---QAKD---TLYHV 430

  Fly   439 IYSGTDDGKVTKFINILSTHPNSTVDR-LKTVVISEMQVLPLG--TPIRELVISTSKNSLVVVSD 500
            :|.||:.|.:.|.:        ||..| |:...:.|:.|||.|  .|:|.|.|..|..:|.|...
Mouse   431 LYIGTESGTILKAL--------STASRSLRGCYLEELHVLPPGRLEPLRSLRILHSARALFVGLS 487

  Fly   501 GSLVSVPLHHCSHIVDCLGCLSLQDPICAWDLQTHECKNLATSQHKFGTKTYLQSLNSTKKAAAL 565
            ..::.|||..||.......||..:||.|.||.:...|..|..|.:   ...::|::.:
Mouse   488 DRVLRVPLERCSAYHSQGACLGARDPYCGWDGKRQLCSTLEDSSN---MSLWIQNITT------- 542

  Fly   566 LCP--HIPRD 573
             ||  ::.||
Mouse   543 -CPVRNVTRD 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_001163178.1	Sema_1A	55..511	CDD:200498	181/477 (38%)
		PSI	510..>537	CDD:214655	9/26 (35%)
Sema5b	XP_006521932.1	Sema	60..496	CDD:387663	179/473 (38%)
		PSI	497..544	CDD:366642	13/57 (23%)
		TSP1	609..662	CDD:214559
		TSP1	667..742	CDD:214559
		TSP1	827..879	CDD:214559
		TSP1	884..936	CDD:214559
		TSP_1	940..981	CDD:387593

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810