Protein Alignment Sema1b and Sema3b

DIOPT Version :9

• Sequence 1: NP_001163178.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_001036244.1
• Gene: Sema3b / 20347
• MGIID: 107561
• Length: 749
• Species: Mus musculus
• Alignment Length: 561
• Identity: 177/561 - (31%)
• Similarity: 279/561 - (49%)
• Gaps: 61/561 - (10%)

  Fly     6 RPSSAAMLVNAIPMILLITLSGLTIVAGWMPDVKPDLQTKQDK--VLAHFIGNSTDYFKIL-DHN 67
            |..:|||    ||.:.|:.::||...|..:|.::...|..|.:  |....:..:..|..:| |..
Mouse     3 RAEAAAM----IPGLALLWVAGLGDTAPNLPRLRLSFQELQARHGVRTFRLERTCCYEALLVDEE 63

  Fly    68 DEFVLVGAKDVIYNVSLNGL-KEIARLEWHSTDADRELCALKGKH-EWDCHNYLRVYALRPNGEV 130
            ...:.|||::.:.::||:.: |...:|.|.:....||.|...||. ..:|.|::::.....:..:
Mouse    64 RGRLFVGAENHVASLSLDNISKRAKKLAWPAPVEWREECNWAGKDIGTECMNFVKLLHTYNHTHL 128

  Fly   131 LLCGTNSYKPRCRHYTPVEVSSEEAGSAGH---AHAMRYEVSRDVEAQGLCPYSPAHNSTYAFAD 192
            |.|||.::.|.|..   |||        ||   ...::.:..:..:.:|..||.|.|.:......
Mouse   129 LACGTGAFHPTCAF---VEV--------GHRLEEPMLQLDRRKLEDGKGKTPYDPRHRAASVLVG 182

  Fly   193 GHLYSATVADFSGGDPLIYRE-----NLRTEQYDLKQLNQPDFVGAI-------ERNGYVLFFFR 245
            ..|||...||..|.|..|:|.     :||||.:|.:.||:|.||...       ..:..:.||||
Mouse   183 EELYSGVTADLMGRDFTIFRSLGQNPSLRTEPHDSRWLNEPKFVKVFWIPESENPDDDKIYFFFR 247

  Fly   246 ELSMEVM-NFGKAVYSRVARVCKNDRGGPYSHGKSWTSFLKARLNCSVPG-EFPFYFDEIQAISP 308
            |.::|.. ..|:...|||.::|:||.||..|....||:||||||.||||| |...:||::|.:.
Mouse   248 ESAVEAAPAMGRMSVSRVGQICRNDLGGQRSLVNKWTTFLKARLVCSVPGVEGDTHFDQLQDVF- 311

  Fly   309 IVESGSKS--LIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWLPVEREQVPKP 371
            ::.|..:.  |:||||:||.....|||||.::::|:..||.|.|..::.....|:..: .:||.|
Mouse   312 LLSSRDRQTPLLYAVFSTSSGVFQGSAVCVYSMNDVRRAFLGPFAHKEGPTHQWVSYQ-GRVPYP 375

  Fly   372 RPGQCVEDSRTLTSIA---------VNFIKNHPLMEEAVPAVHGRPLLTKVNLHHRLTAIAVHPQ 427
            |||.|  .|:|..:.:         :.|.:|||||...|..:.||||..:|...:..|.||. .:
Mouse   376 RPGMC--PSKTFGTFSSTKDFPDDVIQFARNHPLMYNPVLPMGGRPLFLQVGAGYTFTQIAA-DR 437

  Fly   428 VKSLSGAYYDVIYSGTDDGKVTKFINI-LSTHPNSTVDRLKTVVISEMQVLPLGTPIRELVISTS 491
            |.:..| :|||::.|||.|.|.|.|:: ..:.|||     :.:::.|:||......|..:.||:.
Mouse   438 VAAADG-HYDVLFIGTDVGTVLKVISVPKGSRPNS-----EGLLLEELQVFEDSAAITSMQISSK 496

  Fly   492 KNSLVVVSDGSLVSVPLHHCSHI-VDCLGCLSLQDPICAWD 531
            :..|.:.|..::..:.||.|:.: ..|..|...:||.||||
Mouse   497 RQQLYIASRSAVAQIALHRCTALGRACAECCLARDPYCAWD 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_001163178.1	Sema_1A	55..511	CDD:200498	154/487 (32%)
		PSI	510..>537	CDD:214655	9/23 (39%)
Sema3b	NP_001036244.1	Sema	46..516	CDD:417757	154/491 (31%)
		PSI	515..>551	CDD:214655	9/23 (39%)
		Ig	575..665	CDD:416386
		Ig strand A	575..580	CDD:409353
		Ig strand B	585..593	CDD:409353
		Ig strand C	599..605	CDD:409353
		Ig strand C'	607..610	CDD:409353
		Ig strand D	620..624	CDD:409353
		Ig strand E	627..634	CDD:409353
		Ig strand F	640..649	CDD:409353
		Ig strand G	652..665	CDD:409353

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910