Protein Alignment Sema1b and smp-2

DIOPT Version :9

• Sequence 1: NP_001163178.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_491197.3
• Gene: smp-2 / 183905
• WormBaseID: WBGene00004890
• Length: 649
• Species: Caenorhabditis elegans
• Alignment Length: 586
• Identity: 147/586 - (25%)
• Similarity: 252/586 - (43%)
• Gaps: 117/586 - (19%)

  Fly    69 EFVLVGAKDVIYNVSLNGLKEIARLEWHSTDADRELCALKGKHEWDCHNYLRVYALRPNGEVLLC 133
            |:||:|.::.:||:|::.:.||||.||.|:|..|..||...:....|.|::|.|....|..::||
 Worm    55 EYVLLGGRNHVYNISISSMLEIARYEWTSSDEARTNCAAISQTPASCENFIRTYFELTNDTLILC 119

  Fly   134 GTNSYKPRCRHYTPVEVSSEEAGSAGHAHAMRYEVSRDVEAQGLCPYSPAHNSTYAFADGHLYSA 198
            ||::.:|.|..:           ..|:|...|.     :.|.|:.|......:.:..::.::.:.
 Worm   120 GTHALQPTCAEF-----------RKGNAKPQRL-----ISAVGMSPIDADSTAPFIRSNENIITV 168

  Fly   199 TVADFSGGDPLIYREN-------------LRTEQYDLKQLNQPDFVGAIERNGYVLFFFRELSME 250
            .||:.|..:||:.|.|             |||.: .|....|.:|:...:....|||||.|..||
 Worm   169 NVAELSSSEPLLVRRNVIKMWKGIENDVILRTPR-GLSSFEQANFLSMHKVKKEVLFFFSESPME 232

  Fly   251 VMNFGKAVYSRVARVCKNDRGGPYSHGKSWTSFLKARLNCSV--PGEFPFYFDEIQAISPIVESG 313
            ....|....:||.|||::|.||..|:.|.|:|:.|||:.||:  .....|||::...::.
 Worm   233 TEGCGLHKVARVGRVCEDDPGGRLSYNKEWSSYEKARIECSIEETDTDTFYFNQFAGVAE----- 292

  Fly   314 SKSLIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWLPVEREQVPKPRPGQCVE 378
            |.:..|..|.:.:..|..||:|.::...|..:|...:|                  :..|..|
 Worm   293 SPTSFYGAFRSQLAGIGASAICKYSKKVISGSFASGYK------------------ESTPDTC-- 337

  Fly   379 DSRTLTSIAVNFIKNHPLMEEAVPA-----VHGRPLLTKVNLHHRLTAIAVHPQVKSLSGAYYDV 438
             ||......::.|:..||:::.:.|     .||:         .|...:......:.||...||:
 Worm   338 -SRANDIEELSRIRLKPLIKQKISANPIYIFHGK---------DRFVHVLAQEDTRDLSNRAYDI 392

  Fly   439 IYSGTDDGKVTKFINILSTHPNSTVDRLKTVVISEMQVLPLGTPIRELVISTSKN--SLVVVSDG 501
            :|..|:.|.:.|.: :.||      |:.....:: ::|||..:.|.::.:.:..|  .|:|:::.
 Worm   393 LYVATNLGNILKIV-VPST------DKTGRHAVT-LKVLPTNSKIVDMSLYSKNNLEELIVITEQ 449

  Fly   502 SLVSVPLHHCSHIVDCLGCLSLQDPICAWDLQTHECKNLATSQHKFGTKTYLQSLNSTKKAAALL 566
            |::.||...|....:|..||:..||.||| ....:|.::.|.|.|..:
 Worm   450 SVLKVPTATCHLASNCAECLAHGDPHCAW-ADGVDCIDIRTDQRKSAS----------------- 496

  Fly   567 CPHIPRDAPGAETVSF-----VTMAPPPTEEQ-KLLYSNVGSSQGNQP------SLEQQPTGGDD 619
                 :|:...:.|||     |.:||...:|. |:......:.:..:|      ..|...|||.:
 Worm   497 -----QDSGTCDVVSFENHKPVMIAPLKNKESAKIPVCLCETEKQKKPCATEVIQKEIVLTGGSE 556

  Fly   620 F 620
            |
 Worm   557 F 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_001163178.1	Sema_1A	55..511	CDD:200498	119/463 (26%)
		PSI	510..>537	CDD:214655	9/26 (35%)
smp-2	NP_491197.3	Sema	47..429	CDD:214747	112/433 (26%)
		Sema	<390..478	CDD:387663	26/95 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910