Protein Alignment Sema1b and AgaP_AGAP000064

DIOPT Version :9

• Sequence 1: NP_001163178.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: XP_311092.3
• Gene: AgaP_AGAP000064 / 1272211
• VectorBaseID: AGAP000064
• Length: 1919
• Species: Anopheles gambiae
• Alignment Length: 753
• Identity: 151/753 - (20%)
• Similarity: 281/753 - (37%)
• Gaps: 223/753 - (29%)

  Fly    21 LLITLSGLTIVAGWMPDVKPDLQTK-------QDKVLAHFIGNSTDYFKILDHNDEFVLVGAKDV 78
            |||.:|.|..    .|....::.:|       ..::::..:.|||.....:|.:...|.|||.:.
Mosquito    11 LLILISVLCA----QPQANHNVPSKGSNATDLSSRLVSQIVFNSTLNHLAVDRSTGSVYVGAVNK 71

  Fly    79 IYNVS--LNGLKEIARLEWHSTDADRELCAL----KGKHEWDCHNYLRVYALRPNGE-VLLCGTN 136
            :|.:|  ||.|..:..    ....|...|.:    .|..:....|..::..:..|.: :::|| :
Mosquito    72 LYQISNELNILTVVTT----GPQNDSYQCTILECPGGAVKTPMDNVNKMLLIDSNAKNLIVCG-S 131

  Fly   137 SYKPRC--RHYTPVEVSSEEAGSAGHAHAMRYEVSRDVEAQGLCPYSPAHNSTYAF--------- 190
            .::..|  |:...:.:..:|...|..|:.                   |:.||.||
Mosquito   132 LFQGICHIRNLHNISIVEQEVLEAVVANT-------------------ANASTVAFIAPGPPLAS 177

  Fly   191 ADGH-LYSATVADFSGGDPLIYRENL-----RTEQYD-LKQLNQPD-------FVGAIERNGYVL 241
            |:.: ||.|..  |:|..|  ||..:     |:...| |.||....       ||....|..|::
Mosquito   178 AENNVLYVAVT--FTGNSP--YRSEIPAVSSRSLARDRLFQLAASAVTTGTRLFVNNYARETYII 238

  Fly   242 FFFRELSMEVMNF-------------GKAVYSRVARVCKNDRGGPYSHGKSWTSFLKARLNCS-- 291
            .:....|.|..::             .|...:::.|:|::|     ||..|:|   :..::|:
Mosquito   239 NYVYGFSSERFSYFLTTQYKSSSHYASKERITKLVRICQDD-----SHYHSYT---EIPVDCTSK 295

  Fly   292 --------------VPGEFPFYFDEIQAISPIVESGSKSLIYAVF-TTSVNAIPGSAVCAFN--- 338
                          .||.        :....:..:.:..:::||| ..:.|.   ||:|.::
Mosquito   296 DGTKFKTVSAAYVGKPGH--------ELAQSLEITTNDDVLFAVFDAPTANK---SALCVYSLKA 349

  Fly   339 -----VDDILAAFDGEFKSQKDSQSHWLPVEREQVPKPRPGQCVEDSRTLTSIAVNFI---KNHP 395
                 :.:|...::||.....|..|..:|             |:  :..|.:|..:|.   .|.|
Mosquito   350 IRKKFMHNIKKCYNGEGLRGLDYISQNMP-------------CI--ATKLQTIGEDFCGLDVNSP 399

  Fly   396 L-MEEAVPAVHGRPLLTKVNLHHRLTAIAVHPQVKSLSGAYYDVIYSGTDDGKVTKFINILSTHP 459
            | .|:||.:      |..:....|:|::||      .:.:.:.|::.||:.|::.|.:...||
Mosquito   400 LGGEQAVAS------LAVILSEERMTSVAV------TATSNFTVVFIGTETGQLKKIVMESST-- 450

  Fly   460 NSTVDRLKTVVISEMQV----LPLGTPIR-ELVISTSKNSLVVVSDGSLVSVPLHHCSHIVDCLG 519
                        |.||.    :.||:||: ::.:....:.|.::|...|..:.::.||....|..
Mosquito   451 ------------SAMQYAMMNVDLGSPIQPDMYLDPEHDDLYLMSLYKLFKIRIYDCSVYTTCHA 503

  Fly   520 CLSLQDPICAW-DLQT-----HECKN-----LATSQHKFGTKTYLQSL------NSTKKAAALLC 567
            |||.:||.|.| .|:.     :||::     |:...:|.|..|.:.|:      .:|.:...|:.
Mosquito   504 CLSAKDPFCGWCSLENKCSRRYECQDSSKDPLSWLSYKSGKCTTITSVTPHQLQRTTARTLELII 568

  Fly   568 PHIPR-DAPGAETVSFVTMAPPPTEEQKLLYSNVGSSQGNQPSLEQQPTGGDDFGLNKITLTSMD 631
            .::|. ..|.....:|.:|..|       :.:|....:.               |:|..|..:
Mosquito   569 ENLPNLKEPLVCAFTFASMEKP-------IITNATKKRN---------------GVNCTTPRT-- 609

  Fly   632 PDDIMPNLNDPQKSTASVDEIKYASTPSFMLLTTIVFF 669
              |::|.:...:....:...||.:..|. ::.||..||
Mosquito   610 --DLLPQIGYGENHFNATLSIKTSQGPD-IVSTTFTFF 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_001163178.1	Sema_1A	55..511	CDD:200498	106/534 (20%)
		PSI	510..>537	CDD:214655	11/32 (34%)
AgaP_AGAP000064	XP_311092.3	Sema_plexin_like	51..492	CDD:200497	104/528 (20%)
		PSI	494..546	CDD:279745	16/51 (31%)
		PSI	645..>673	CDD:279745	151/753 (20%)
		PSI	804..861	CDD:279745
		IPT_plexin_repeat1	863..955	CDD:238585
		IPT_plexin_repeat2	956..1041	CDD:238584
		IPT	1057..1153	CDD:301692
		Plexin_cytopl	1326..1890	CDD:285529

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910