Protein Alignment Sema1b and Sema3d

DIOPT Version :9

• Sequence 1: NP_001163178.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: NP_083158.3
• Gene: Sema3d / 108151
• MGIID: 1860118
• Length: 777
• Species: Mus musculus
• Alignment Length: 569
• Identity: 183/569 - (32%)
• Similarity: 286/569 - (50%)
• Gaps: 63/569 - (11%)

  Fly    19 MILLITLSGLTIVAGWMPDVKPDLQ-TKQDKVLAH----FIGNS--TDY-FKILDHNDEFVLVGA 75
            |:|::|:..|.:......:: |.|: |.:|.:|::    |:|:|  .|: ..:||.....:|:||
Mouse    23 MMLIMTVLFLPVTETSKQNI-PRLKLTYKDLLLSNTCIPFLGSSEGLDFQTLLLDEERGILLLGA 86

  Fly    76 KDVIYNVSLNGL-KEIARLEWHSTDADRELCALKGKH-EWDCHNYLRVYALRPNGE--VLLCGTN 136
            ||.::.:||..| |...::.|.:.....|||.|.||. ..:|.|::||  |:|..:  |.:|||.
Mouse    87 KDHVFLLSLVDLNKNFKKIYWPAAKERVELCKLAGKDANAECANFIRV--LQPYNKTHVYVCGTG 149

  Fly   137 SYKPRCRHYTPVEVSSEEAGSAGHAHAMRYEVSRDVEAQGL-CPYSPAHNSTYAFADGHLYSATV 200
            ::.|.| .|..:..:.||.......|        ::|:..| ||:.|.........|.||||.|.
Mouse   150 AFHPLC-GYIDLGANKEELIFKLDTH--------NLESGRLKCPFDPQQPFASVMTDEHLYSGTA 205

  Fly   201 ADFSGGDPLIYR--------ENLRTEQYDLKQLNQPDFVGAI-------ERNGYVLFFFRELSME 250
            :||.|.|....|        .::||:..:...||...|:|..       ..:..:.|||||.|.|
Mouse   206 SDFLGKDTAFTRSLGLMQDHHSIRTDISEHHWLNGAKFIGTFPIPDTYNPDDDKIYFFFRESSQE 270

  Fly   251 VMNFGKAVYSRVARVCKNDRGGPYSHGKSWTSFLKARLNCSVPGE--FPFYFDEIQAISPIVESG 313
            .....:::.|||.||||||.||..|....||:||||||.||:||.  ...:|||:|.|..:....
Mouse   271 GSTSDRSILSRVGRVCKNDVGGQRSLINKWTTFLKARLICSIPGSDGADTHFDELQDIYLLPTRD 335

  Fly   314 SKS-LIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWLPVEREQVPKPRPGQC- 376
            .:: ::|.||||:.:...|||||.:::.||.|.|:|.:..::.:...|:..: .::|.||||.|
Mouse   336 ERNPVVYGVFTTTSSIFKGSAVCVYSMADIRAVFNGPYAHKESADHRWVQYD-GRIPYPRPGTCP 399

  Fly   377 -------VEDSRTLTSIAVNFIKNHPLMEEAVPAVHGRPLLTKVNLHHRLTAIAVHPQVKSLSGA 434
                   ::.:|......::||:.||:|.::|..|.|.|...::|:.:|||.|.|...|  ....
Mouse   400 SKTYDPLIKSTRDFPDDVISFIRRHPVMYKSVYPVAGAPTFKRINVDYRLTQIVVDHVV--AEDG 462

  Fly   435 YYDVIYSGTDDGKVTKFINILSTHPNSTVDRLKTVVISEMQVLPLGTPIRELVISTSKNSLVVVS 499
            .|||::.|||.|.|.|.::|.....|     ::.||:.|:||....|.|..:.:|..:..|.|.|
Mouse   463 QYDVMFLGTDIGTVLKVVSISKEKWN-----MEEVVLEELQVFKHPTAILNMELSLKQQQLYVGS 522

  Fly   500 DGSLVSVPLHHC-SHIVDCLGCLSLQDPICAWDLQTHECKNLA-TSQHK 546
            ...||.:.||.| ::...|..|...:||.||||  .:.|...| ||:.:
Mouse   523 WDGLVQLSLHRCDTYGKACADCCLARDPYCAWD--GNACSRYAPTSKRR 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_001163178.1	Sema_1A	55..511	CDD:200498	160/489 (33%)
		PSI	510..>537	CDD:214655	9/27 (33%)
Sema3d	NP_083158.3	Sema_3D	61..534	CDD:200513	161/491 (33%)
		PSI	533..570	CDD:214655	13/39 (33%)
		Ig_Semaphorin_classIII	596..686	CDD:143279
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	740..777

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11036
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910