Protein Alignment Sema1b and sema5b

DIOPT Version :10

• Sequence 1: NP_611244.1
• Gene: Sema1b / 37007
• FlyBaseID: FBgn0016059
• Length: 770
• Species: Drosophila melanogaster
• Sequence 2: XP_031748739.1
• Gene: sema5b / 100493363
• XenbaseID: XB-GENE-959729
• Length: 1104
• Species: Xenopus tropicalis
• Alignment Length: 540
• Identity: 200/540 - (37%)
• Similarity: 286/540 - (52%)
• Gaps: 70/540 - (12%)

  Fly    50 LAHFIGNST-----DYFKI-LDHNDEFVLVGAKDVIYNVSLNGLKEIARLEWHSTDADRELCALK 108
            |..::.|.|     |:.:: ||.|...::|||::.::.:||:.:..|...||.|.:..:..|..|
 Frog    61 LKPWLSNFTFSDVRDFSQLALDLNRNQLIVGARNYLFRLSLHNVSLIQAAEWSSDEDTQRSCQSK 125

  Fly   109 GKHEWDCHNYLRVYALRPNGE-VLLCGTNSYKPRCRHYTPVEVSSEEAGSAGHAHAMRYEVSRDV 172
            ||.|.:|.||:||  |..:|: |..||||::.|.|        :|.:.|:..       :|...:
 Frog   126 GKTEDECQNYVRV--LIVSGKRVFTCGTNAFSPVC--------TSRQVGNLS-------KVIEKI 173

  Fly   173 EAQGLCPYSPAHNSTYAFAD-GHLYSATVADFSGGDPLIYRE-----NLRTEQYDLKQLNQPDFV 231
            .....|||.|.||||..... |.||:|||.||||.||:|||.     .|||.||:.|.||:|:||
 Frog   174 NGVARCPYDPRHNSTAVMTTRGELYAATVIDFSGRDPVIYRSLGSVPPLRTAQYNSKWLNEPNFV 238

  Fly   232 GAIERNGYVLFFFRELSMEVMNFGKAVYSRVARVCKNDRGGPYSHGKSWTSFLKARLNCSVPGEF 296
            .|.:...:..|||||.::| .:.||.||||||||||||.||.:....:||:|:|||||||.|||.
 Frog   239 AAYDIGIFTYFFFRENAVE-HDCGKTVYSRVARVCKNDYGGRFLLEDTWTTFMKARLNCSRPGEI 302

  Fly   297 PFYFDEIQAISPIVESGSKSLIYAVFTTSVNAIPGSAVCAFNVDDILAAFDGEFKSQKDSQSHWL 361
            |||::|:|:...:.|   :.|||.||||:||:|..|||||||:..|..||:|.|:.|::.:|.||
 Frog   303 PFYYNELQSTFLLPE---QDLIYGVFTTNVNSIAASAVCAFNLSAITQAFNGPFRYQENPRSAWL 364

  Fly   362 PVEREQVPKPRPGQCVEDS--RTLTSIAVNFIKNHPLMEEAVPAVHGRPLLTKVNLHHRLTAIAV 424
            |. ...:|..:.|...:||  ..||..::...:...||.:.|..|...||:|:.::  |.:.:.|
 Frog   365 PT-INPIPNFQCGILNDDSPNENLTERSLQDAQRLFLMNDVVQPVSVEPLVTQDSV--RFSKLVV 426

  Fly   425 HPQVKSLSGAYYDVIYSGTDDGKVTKFINILSTHPNSTVDR-LKTVVISEMQVLPLG--TPIREL 486
              .:.......|.|:|.||:.|.:.|.:        ||.:| |::..:.||.:||:|  .|||.|
 Frog   427 --DIVQGKDTLYHVMYIGTEHGTILKAL--------STANRSLRSCYLEEMHILPIGQQEPIRSL 481

  Fly   487 VISTSKNSLVVVSDGSLVSVPLHHCSHI---VDCLGCLSLQDPICAWDLQTHECKNLATSQHKFG 548
            .|..|..||.|..:..::.|||..||..   .|.||.   :||.|.||.:...|.. |...:..|
 Frog   482 QILHSNRSLFVGLNNGVLKVPLERCSIYRTEGDRLGA---RDPYCGWDSKKKRCTPXAYPHYITG 543

  Fly   549 TKTYLQSLNSTKKAAALLCP 568
            .:.            .|.||
 Frog   544 PRN------------TLSCP 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema1b	NP_611244.1	Sema_1A	55..511	CDD:200498	183/473 (39%)
		PSI	510..>537	CDD:214655	10/29 (34%)
sema5b	XP_031748739.1	Sema_5B	68..504	CDD:200525	181/469 (39%)
		PSI	505..>533	CDD:214655	10/30 (33%)
		TSP1	613..674	CDD:214559
		TSP1	679..725	CDD:214559
		TSP1	810..862	CDD:214559
		TSP1	867..919	CDD:214559
		TSP1	922..963	CDD:214559